Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C3K3L6

- TRMB_PSEFS

UniProt

C3K3L6 - TRMB_PSEFS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Pseudomonas fluorescens (strain SBW25)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei71 – 711S-adenosyl-L-methionineUniRule annotation
Binding sitei96 – 961S-adenosyl-L-methionineUniRule annotation
Binding sitei123 – 1231S-adenosyl-L-methionineUniRule annotation
Active sitei146 – 1461By similarity
Binding sitei146 – 1461S-adenosyl-L-methionineUniRule annotation
Binding sitei150 – 1501SubstrateUniRule annotation
Binding sitei182 – 1821SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:PFLU_5772
OrganismiPseudomonas fluorescens (strain SBW25)
Taxonomic identifieri216595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002332: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 241241tRNA (guanine-N(7)-)-methyltransferasePRO_1000213442Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi216595.PFLU5772.

Structurei

3D structure databases

ProteinModelPortaliC3K3L6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni219 – 2224Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
KOiK03439.
OMAiMSTENEN.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3K3L6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTESNETPNT PEAGDESKHR RIKSFVMRAG RMTEGQQKGL EQGTPLFVLP
60 70 80 90 100
LADAPVDYDQ VFGRSAPRSL EIGFGMGHSL LEMAAAAPDQ DFIGVEVHRP
110 120 130 140 150
GVGALLNGVL TQGLTNLRVY DCDAIEVLNR CIADNSLDRL MLFFPDPWHK
160 170 180 190 200
ARHHKRRIVQ ASFAELVRSK LKVGGILHMA TDWEPYAEYM LEVMNVAPGY
210 220 230 240
RNLAEDGKCV PRPAERPITK FERRGERLGH GVWDLKFEKL A
Length:241
Mass (Da):27,007
Last modified:June 16, 2009 - v1
Checksum:i1AEDE04DFA5CC234
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY53159.1.
RefSeqiYP_002875262.1. NC_012660.1.

Genome annotation databases

EnsemblBacteriaiCAY53159; CAY53159; PFLU_5772.
GeneIDi7821573.
KEGGipfs:PFLU5772.
PATRICi19905664. VBIPseFlu98510_5894.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY53159.1 .
RefSeqi YP_002875262.1. NC_012660.1.

3D structure databases

ProteinModelPortali C3K3L6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 216595.PFLU5772.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAY53159 ; CAY53159 ; PFLU_5772 .
GeneIDi 7821573.
KEGGi pfs:PFLU5772.
PATRICi 19905664. VBIPseFlu98510_5894.

Phylogenomic databases

eggNOGi COG0220.
KOi K03439.
OMAi MSTENEN.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SBW25.

Entry informationi

Entry nameiTRMB_PSEFS
AccessioniPrimary (citable) accession number: C3K3L6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: October 1, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3