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C3K3D2 (BETB_PSEFS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase
Short name=BADH
EC=1.2.1.8
Gene names
Name:betB
Ordered Locus Names:PFLU_5685
OrganismPseudomonas fluorescens (strain SBW25) [Complete proteome] [HAMAP]
Taxonomic identifier216595 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length490 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processbetaine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 490490Betaine aldehyde dehydrogenase HAMAP MF_00804
PRO_1000213000

Regions

Nucleotide binding229 – 2346NAD By similarity

Sites

Active site2521 By similarity
Active site2861 By similarity

Sequences

Sequence LengthMass (Da)Tools
C3K3D2 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: 5913B4CF5B36E2E1

FASTA49053,156
        10         20         30         40         50         60 
MARFDLQKLY IDGGYSDAGS DATFEAINPA NGEVLAQVQR ATKEDVERAV VSAEKGQKIW 

        70         80         90        100        110        120 
AAMTAMERSR ILRRAVDILR ERNDELAALE TLDTGKAFSE TQYVDVVTGA DVLEYYAGLV 

       130        140        150        160        170        180 
PAIEGEQIPL RDTSFVYTRR EPLGVVAGIG AWNYPIQIAL WKSAPALAAG NAMIFKPSEV 

       190        200        210        220        230        240 
TSLTTLKLAE IYTEAGVPAG VFNVLTGSGR EVGTWLTEHP RIEKVSFTGG TDTGKKVMAS 

       250        260        270        280        290        300 
ASSSSLKEVT MELGGKSPLI VFEDADLDRA ADIAMMANFY SSGQVCTNGT RVFVPKHLQA 

       310        320        330        340        350        360 
AFEAKIVERV ARIRVGDPQD ENTNFGPLVS FAHMESVLGY IAKGKEQGAR LLCGGDRLTD 

       370        380        390        400        410        420 
GDFAKGAYVA PTVFTDCTDE MTIVREEIFG PVMSILTYET EEEVIRRAND TDFGLAAGLV 

       430        440        450        460        470        480 
TKDLNRAHRV IHQLEAGICW INAWGESDAK MPVGGYKQSG VGRENGISSL NNFTRIKSVQ 

       490 
VELGDYASVF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM181176 Genomic DNA. Translation: CAY53022.1.
RefSeqYP_002875178.1. NC_012660.1.

3D structure databases

ProteinModelPortalC3K3D2.
ModBaseSearch...

Protein-protein interaction databases

STRINGC3K3D2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7816696.
GenomeReviewsGene locus PFLU_5685 in contig AM181176_GR.
KEGGpfs:PFLU5685.
PATRIC19905492. VBIPseFlu98510_5808.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAAHRTIHR.
ProtClustDBPRK13252.

Enzyme and pathway databases

BioCycPFLU216595:PFLU5685-MONOMER.

Family and domain databases

HAMAPMF_00804. BADH.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00130.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_PSEFS
AccessionPrimary (citable) accession number: C3K3D2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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