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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Pseudomonas fluorescens (strain SBW25)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei390 – 3901UniRule annotation
Active sitei518 – 5181UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PFLU_5243
OrganismiPseudomonas fluorescens (strain SBW25)
Taxonomic identifieri216595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002332: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 554554Glucose-6-phosphate isomerasePRO_1000206370Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi216595.PFLU5243.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3K249-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYYRTPHDV TALPAWQALN QHRQAMQDFS MREAFNADPQ RFSQFTLSSC
60 70 80 90 100
GLFLDYSKNL ITSETRDLLV GLAKEVGLKD AINSLYAGEP VNSSEGRPAL
110 120 130 140 150
HTALRRPVGD KLSVNGVNIM PDVHKVLNQI TDLVGRIHDG LWRGYTEKPI
160 170 180 190 200
TDVVNIGIGG SFLGPELVSE ALLSYAHKGV RCHYLANIDG SEFHELTMKL
210 220 230 240 250
RAETTLFIVS SKSFNTLETL KNAQAARAWY LAQGGSEAEL YRHFIAVSSN
260 270 280 290 300
NAAAVAFGIR EENIFPMWDW VGGRYSLWSA IGLPIALAIG MSNFKELLSG
310 320 330 340 350
AYTMDQHFQN APFEANMPVL LGLLGVWYGN FWGAQSHAIL PYDHYLRNIT
360 370 380 390 400
KHLQQLDMES NGKSVRQDGT PVATDTGPVI WGGVGCNGQH AYHQLLHQGT
410 420 430 440 450
QLIPADFIVP IVSFNPVSDH HQWLYANCLS QSQALMLGKT RVEAEAELRD
460 470 480 490 500
KGIPEDEVQK LAPHKVIPGN RPSNTLVVER ISPRRLGALV AMYEHKVFVQ
510 520 530 540 550
SVIWGINAFD QWGVELGKEL GKGVYNRLTG AEETSAEDAS TQGLINYFRG

RHRG
Length:554
Mass (Da):61,423
Last modified:June 16, 2009 - v1
Checksum:iF058FC5D7A4D480B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY52336.1.
RefSeqiYP_002874745.1. NC_012660.1.

Genome annotation databases

EnsemblBacteriaiCAY52336; CAY52336; PFLU_5243.
GeneIDi7821116.
KEGGipfs:PFLU5243.
PATRICi19904602. VBIPseFlu98510_5375.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY52336.1.
RefSeqiYP_002874745.1. NC_012660.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216595.PFLU5243.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAY52336; CAY52336; PFLU_5243.
GeneIDi7821116.
KEGGipfs:PFLU5243.
PATRICi19904602. VBIPseFlu98510_5375.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SBW25.

Entry informationi

Entry nameiG6PI_PSEFS
AccessioniPrimary (citable) accession number: C3K249
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: March 4, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.