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Protein

Kynurenine formamidase

Gene

kynB

Organism
Pseudomonas fluorescens (strain SBW25)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.UniRule annotationSAAS annotation

Catalytic activityi

N-formyl-L-kynurenine + H2O = formate + L-kynurenine.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. arylformamidase activity Source: UniProtKB-HAMAP
  2. formamidase activity Source: InterPro

GO - Biological processi

  1. tryptophan catabolic process to kynurenine Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Tryptophan catabolismUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00333; UER00454.

Names & Taxonomyi

Protein namesi
Recommended name:
Kynurenine formamidaseUniRule annotationSAAS annotation (EC:3.5.1.9UniRule annotationSAAS annotation)
Short name:
KFAUniRule annotation
Short name:
KFaseUniRule annotation
Alternative name(s):
ArylformamidaseUniRule annotation
N-formylkynurenine formamidaseUniRule annotation
Gene namesi
Name:kynBUniRule annotation
Ordered Locus Names:PFLU_5199Imported
OrganismiPseudomonas fluorescens (strain SBW25)Imported
Taxonomic identifieri216595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002332 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi216595.PFLU5199.

Structurei

3D structure databases

ProteinModelPortaliC3K207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KynB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1878.
KOiK07130.
OMAiTLWDITP.
OrthoDBiEOG67T5JJ.

Family and domain databases

HAMAPiMF_01969. KynB.
InterProiIPR007325. KFase.
IPR017484. Kynurenine_formamidase_bac.
[Graphical view]
PfamiPF04199. Cyclase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03035. trp_arylform. 1 hit.

Sequencei

Sequence statusi: Complete.

C3K207-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPIKTWWDI SPPLSTATPT WPGDTPFQEE RVWQFGPECP VNVGRITLSP
60 70 80 90 100
HTGAHVDAPL HYSADGAPIG EVSLDVYMGP CRVLHCLDSG ALVQPHQLEG
110 120 130 140 150
RVDNVPERVL LRTYPQAPLT EWDADFTAIA PQTIELLASL GVRLIGIDTP
160 170 180 190 200
SLDPQQSKTM DSHNAVARHG MAILEGIVLD DVPEGDYELI ALPLRFAHLD
210
ASPVRAILRP LKEPTR
Length:216
Mass (Da):23,695
Last modified:June 16, 2009 - v1
Checksum:iD54D84404CA0D431
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY52267.1.
RefSeqiWP_015885871.1. NC_012660.1.
YP_002874703.1. NC_012660.1.

Genome annotation databases

EnsemblBacteriaiCAY52267; CAY52267; PFLU_5199.
GeneIDi7818631.
KEGGipfs:PFLU5199.
PATRICi19904506. VBIPseFlu98510_5332.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY52267.1.
RefSeqiWP_015885871.1. NC_012660.1.
YP_002874703.1. NC_012660.1.

3D structure databases

ProteinModelPortaliC3K207.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216595.PFLU5199.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAY52267; CAY52267; PFLU_5199.
GeneIDi7818631.
KEGGipfs:PFLU5199.
PATRICi19904506. VBIPseFlu98510_5332.

Phylogenomic databases

eggNOGiCOG1878.
KOiK07130.
OMAiTLWDITP.
OrthoDBiEOG67T5JJ.

Enzyme and pathway databases

UniPathwayiUPA00333; UER00454.

Family and domain databases

HAMAPiMF_01969. KynB.
InterProiIPR007325. KFase.
IPR017484. Kynurenine_formamidase_bac.
[Graphical view]
PfamiPF04199. Cyclase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03035. trp_arylform. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SBW25Imported.

Entry informationi

Entry nameiC3K207_PSEFS
AccessioniPrimary (citable) accession number: C3K207
Entry historyi
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: April 29, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.