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Protein

60 kDa chaperonin

Gene

groL

Organism
Pseudomonas fluorescens (strain SBW25)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:PFLU_4987
OrganismiPseudomonas fluorescens (strain SBW25)
Taxonomic identifieri216595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002332 Componenti: Chromosome

Subcellular locationi

C3K1A0:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002122061 – 54860 kDa chaperoninAdd BLAST548

Proteomic databases

PRIDEiC3K1A0.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi216595.PFLU4987.

Structurei

3D structure databases

SMRiC3K1A0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

C3K1A0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKEVKFGD SARKKMLTGV NVLADAVKAT LGPKGRNVII EKSFGAPTIT
60 70 80 90 100
KDGVSVAKEI ELEDRFENMG AQLVKDVASR ANDDAGDGTT TATVLAQAIV
110 120 130 140 150
NEGYKAVAAG MNPMDLKRGI DKATIAIVAE LKNLSKPCAD TKAIAQVGTI
160 170 180 190 200
SANSDSSIGD IIAEAMEKVG KEGVITVEEG TGLENELSVV EGMQFDRGYL
210 220 230 240 250
SPYFVNKPET MVAELDSPLI LLVDKKISNI REMLPVLEAV AKAGRPLLIV
260 270 280 290 300
SEDVEGEALA TLVVNNMRGI VKVAAVKAPG FGDRRKAMLQ DIAVLTGGTV
310 320 330 340 350
ISEEIGLSLE SATLENLGSA KRVTISKENT IIVDGAGVEQ DIQARITQIR
360 370 380 390 400
AQVAETSSDY DREKLQERLA KLSGGVAVIK VGAGSEVEMK EKKARVEDAL
410 420 430 440 450
HATRAAVEEG VVPGGGVALI RALEALTNLT GDNADQNVGI AVLRRAVEAP
460 470 480 490 500
LRQIAANSGD EPSVVVNEVK NGKGNYGYNA ATGVYGDMIE MGILDPTKVT
510 520 530 540
RSALQAAASI GGLILTTEAA IADKPKAEGA GGGGMPDMGG MGGMGGMM
Length:548
Mass (Da):56,966
Last modified:June 16, 2009 - v1
Checksum:iF997C43CE354DB69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY51939.1.
RefSeqiWP_015885679.1. NC_012660.1.

Genome annotation databases

EnsemblBacteriaiCAY51939; CAY51939; PFLU_4987.
KEGGipfs:PFLU_4987.
PATRICifig|216595.4.peg.5122.

Similar proteinsi

Entry informationi

Entry nameiCH60_PSEFS
AccessioniPrimary (citable) accession number: C3K1A0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: October 25, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families