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Protein

Glutaminase

Gene

glsA

Organism
Pseudomonas fluorescens (strain SBW25)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei61 – 611SubstrateUniRule annotation
Binding sitei111 – 1111SubstrateUniRule annotation
Binding sitei155 – 1551SubstrateUniRule annotation
Binding sitei162 – 1621SubstrateUniRule annotation
Binding sitei186 – 1861SubstrateUniRule annotation
Binding sitei238 – 2381SubstrateUniRule annotation
Binding sitei256 – 2561Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:PFLU_3587
OrganismiPseudomonas fluorescens (strain SBW25)
Taxonomic identifieri216595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002332 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302GlutaminasePRO_1000205063Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi216595.PFLU3587.

Structurei

3D structure databases

ProteinModelPortaliC3JXF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

C3JXF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAMLSSILD EVRPLIGLGK VADYIPALAD VPANQLGIAV YGNDGSAYRA
60 70 80 90 100
GDADTLFSVQ SISKVFSLVQ AIDHGGETIW ERLGHEPSGQ PFNSMVQLEF
110 120 130 140 150
ERGRPRNPFI NAGALVICDI NQSRFAVPIL SMRDFVRRLS GNPHILVNSV
160 170 180 190 200
VAESEAQHGA RNAAMAYLMK SFGNFHNDVD AVLHSYFNYC ALQMSCVDLA
210 220 230 240 250
KAFSFLANEG TSAHSGEQIL TARQTRQVNS IMATSGLYDE AGNFAYRVGL
260 270 280 290 300
PGKSGVGGGI VAVVPGQFTV CVWSPELNAA GNSLAGMKAL ELLSERIGWS

VF
Length:302
Mass (Da):32,403
Last modified:June 16, 2009 - v1
Checksum:i515B8C69ACA72AF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY49806.1.
RefSeqiWP_012724735.1. NC_012660.1.

Genome annotation databases

EnsemblBacteriaiCAY49806; CAY49806; PFLU_3587.
GeneIDi7820752.
KEGGipfs:PFLU3587.
PATRICi19901270. VBIPseFlu98510_3736.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM181176 Genomic DNA. Translation: CAY49806.1.
RefSeqiWP_012724735.1. NC_012660.1.

3D structure databases

ProteinModelPortaliC3JXF9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216595.PFLU3587.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAY49806; CAY49806; PFLU_3587.
GeneIDi7820752.
KEGGipfs:PFLU3587.
PATRICi19901270. VBIPseFlu98510_3736.

Phylogenomic databases

eggNOGiCOG2066.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SBW25.

Entry informationi

Entry nameiGLSA_PSEFS
AccessioniPrimary (citable) accession number: C3JXF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 16, 2009
Last modified: July 22, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.