C3E8G5 (C3E8G5_BACTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259 RuleBase RU003981
EC=2.1.2.10 HAMAP MF_00259 RuleBase RU003981

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
ORF Names:	bthur0005_39600 EMBL EEM46157.1

Organism

Bacillus thuringiensis serovar pakistani str. T13001 EMBL EEM46157.1

Taxonomic identifier

527027 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903 Methyltransferase EMBL EEM46157.1 Transferase
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3E8G5 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: B20A4A96ACF8D4BA	FASTA	366	40,225
	10 20 30 40 50 60 MITLQRTPLF DVYAKYGGKT IDFGGWELPV QFSSIKEEHE AVRTAAGLFD VSHMGEVEVK 70 80 90 100 110 120 GVDSLAFLQR VVTNDVSTLK VGGAQYTAMC YENGGTVDDL LIYKRGEEDY LLVINASNIE 130 140 150 160 170 180 KDYEWLASHV IGDATVVNVS SEVAQLAIQG PKAEGILQKV VSEDLKEIKF FKFKNDILVD 190 200 210 220 230 240 GIPALVSRTG YTGEDGFEIY CKSEDAAKLW EKLLEVGAEE GLKACGLGAR DTLRFEATLP 250 260 270 280 290 300 LYGQELSKDI TPIEAGIGFA VKTNKEADFF GKATLKEQKE NGAPRKLVGI EVIERGIPRT 310 320 330 340 350 360 HYPVFIGEEK IGEVTSGTQS PTLKKSIGLA LIDVKYAAVD TEVEIEIRNK RVKAVVVPTP FYKRSK

References

[1]

"Annotation of the Bacillus thuringiensis T13001 genome." Read T.D., Akmal A., Bishop-Lilly K., Chen P.E., Cook C., Kiley M.P., Lentz S., Mateczun A., Nagarajan N., Nolan N., Osborne B.I., Pop M., Sozhamannan S., Stewart A.C., Sulakvelidze A., Thomason B., Willner K., Zwick M.E. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: T13001 EMBL EEM46157.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACNC01000148 Genomic DNA. Translation: EEM46157.1.
3D structure databases
ProteinModelPortal	C3E8G5.
SMR	C3E8G5. Positions 4-364.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000237562; EBBACP00000234287; EBBACG00000241562.
PATRIC	28921839. VBIBacThu54181_1503.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C3E8G5_BACTU

Accession

Primary (citable) accession number: C3E8G5

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)