C3E0I8 (C3E0I8_BACTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134
ORF Names:	bthur0005_11350 EMBL EEM48932.1

Organism

Bacillus thuringiensis serovar pakistani str. T13001 EMBL EEM48932.1

Taxonomic identifier

527027 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	253 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134 SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134 SAAS SAAS013798
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134 SAAS SAAS013798
Molecular function	Decarboxylase HAMAP MF_00134 SAAS SAAS013798 Lyase
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3E0I8 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 2519649E1A8081C8	FASTA	253	28,290
	10 20 30 40 50 60 MGTILDKIVE QKKKEVAELY EIYTPVKTKR KTQSLVEALQ QFTVIAEVKR ASPSKGDINL 70 80 90 100 110 120 HVDVRKQVGT YEKCGAGAVS VLTDGQFFKG SFHDLQTARE ESNIPLLCKD FIIDKIQIDR 130 140 150 160 170 180 AYEAGADIIL LIVAALTKEK LKELYSYVLE KGLEAIVEVH DEQELETAIV LNPHVIGINN 190 200 210 220 230 240 RNLKTFEVDL SQTEKLGKRL NEEKLLWISE SGIHSKEDII RVKRAGAKGV LVGEALMTSS 250 SISSFFEDCK VNI

References

[1]

"Annotation of the Bacillus thuringiensis T13001 genome." Read T.D., Akmal A., Bishop-Lilly K., Chen P.E., Cook C., Kiley M.P., Lentz S., Mateczun A., Nagarajan N., Nolan N., Osborne B.I., Pop M., Sozhamannan S., Stewart A.C., Sulakvelidze A., Thomason B., Willner K., Zwick M.E. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: T13001 EMBL EEM48932.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACNC01000048 Genomic DNA. Translation: EEM48932.1.
3D structure databases
ProteinModelPortal	C3E0I8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000242335; EBBACP00000236731; EBBACG00000242418.
PATRIC	28916093. VBIBacThu54181_4234.
Family and domain databases
HAMAP	MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3E0I8_BACTU

Accession

Primary (citable) accession number: C3E0I8

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)