C2GT97 (C2GT97_BIFLN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphopantetheine adenylyltransferase HAMAP MF_00151
EC=2.7.7.3 HAMAP MF_00151

Alternative name(s):
Dephospho-CoA pyrophosphorylase HAMAP MF_00151
Pantetheine-phosphate adenylyltransferase HAMAP MF_00151

Gene names

Name:	coaD HAMAP MF_00151 EMBL EEI81776.1
ORF Names:	HMPREF0175_0244 EMBL EEI81776.1

Organism

Bifidobacterium longum subsp. longum ATCC 55813 EMBL EEI81776.1

Taxonomic identifier

548480 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151
Catalytic activity	ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151
Subunit structure	Homohexamer By similarity. HAMAP MF_00151
Subcellular location	Cytoplasm By similarity HAMAP MF_00151.
Sequence similarities	Belongs to the bacterial CoaD family. HAMAP MF_00151
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis HAMAP MF_00151
Cellular component	Cytoplasm HAMAP MF_00151
Ligand	ATP-binding HAMAP MF_00151 Nucleotide-binding
Molecular function	Nucleotidyltransferase HAMAP MF_00151 EMBL EEI81776.1 Transferase
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW pantetheine-phosphate adenylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C2GT97 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 4622E8EDCBF407BD	FASTA	166	17,838
	10 20 30 40 50 60 MTIAVCPGSY DPVTAGHLDV IERSARFFDE VHVVVAVNAA KTPMFSEATR VDVIRRALDK 70 80 90 100 110 120 AGCKNVTVSS TDGLITDYCK KVGATVIIKG LRQNGDYEAE LGMALVNRKL AGIETLFLPA 130 140 150 160 DPILEHISSS IVKDVARHGG DVTGMVPDCV VPMLADALAE ERQRKD

References

[1]

Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L., Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G., Francisco L., Fu Q., Gubbala S., Hale W., Han Y. , Hemphill L., Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A., Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R., Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R., Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P., Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y., Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L., Zhou C., Zhu D., Muzny D., Worley K., Gibbs R. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC 55813 EMBL EEI81776.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACHI01000005 Genomic DNA. Translation: EEI81776.1.
3D structure databases
ProteinModelPortal	C2GT97.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	36945214. VBIBifLon7869_1860.
Family and domain databases
HAMAP	MF_00151. PPAT_bact. [Tree]
InterPro	IPR004821. Cyt_trans-rel. IPR004820. Cytidylyltransf. IPR001980. LPS_biosynth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01467. CTP_transf_2. 1 hit. [Graphical view]
PRINTS	PR01020. LPSBIOSNTHSS.
TIGRFAMs	TIGR01510. CoaD_prev_kdtB. 1 hit. TIGR00125. Cyt_tran_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C2GT97_BIFLN

Accession

Primary (citable) accession number: C2GT97

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)