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Protein
Submitted name:

Uncharacterized protein

Gene

epi-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Biological processi

  • axonal defasciculation Source: WormBase
  • basement membrane organization Source: WormBase
  • cell adhesion Source: InterPro
  • cell migration Source: WormBase
  • neuron migration Source: WormBase
  • positive regulation of endopeptidase activity Source: WormBase
  • positive regulation of locomotion Source: WormBase
  • regulation of cell proliferation Source: WormBase
  • reproduction Source: WormBase
  • response to heat Source: WormBase
  • response to misfolded protein Source: WormBase

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:epi-1Imported
ORF Names:CELE_K08C7.3Imported, K08C7.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiK08C7.3d ; CE43590 ; WBGene00001328 ; epi-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500291240628 – 3663Sequence analysisAdd BLAST3636

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi322 ↔ 331PROSITE-ProRule annotation
Disulfide bondi394 ↔ 403PROSITE-ProRule annotation
Disulfide bondi447 ↔ 456PROSITE-ProRule annotation
Disulfide bondi472 ↔ 484PROSITE-ProRule annotation
Disulfide bondi474 ↔ 491PROSITE-ProRule annotation
Disulfide bondi493 ↔ 502PROSITE-ProRule annotation
Disulfide bondi519 ↔ 531PROSITE-ProRule annotation
Disulfide bondi521 ↔ 538PROSITE-ProRule annotation
Disulfide bondi540 ↔ 549PROSITE-ProRule annotation
Disulfide bondi564 ↔ 576PROSITE-ProRule annotation
Disulfide bondi566 ↔ 583PROSITE-ProRule annotation
Disulfide bondi585 ↔ 594PROSITE-ProRule annotation
Disulfide bondi610 ↔ 622PROSITE-ProRule annotation
Disulfide bondi612 ↔ 629PROSITE-ProRule annotation
Disulfide bondi631 ↔ 640PROSITE-ProRule annotation
Disulfide bondi656 ↔ 668PROSITE-ProRule annotation
Disulfide bondi676 ↔ 685PROSITE-ProRule annotation
Disulfide bondi726 ↔ 735PROSITE-ProRule annotation
Disulfide bondi779 ↔ 788PROSITE-ProRule annotation
Disulfide bondi809 ↔ 821PROSITE-ProRule annotation
Disulfide bondi811 ↔ 828PROSITE-ProRule annotation
Disulfide bondi830 ↔ 839PROSITE-ProRule annotation
Disulfide bondi1406 ↔ 1418PROSITE-ProRule annotation
Disulfide bondi1408 ↔ 1425PROSITE-ProRule annotation
Disulfide bondi1427 ↔ 1436PROSITE-ProRule annotation
Disulfide bondi1469 ↔ 1478PROSITE-ProRule annotation
Disulfide bondi1520 ↔ 1529PROSITE-ProRule annotation
Disulfide bondi1545 ↔ 1557PROSITE-ProRule annotation
Disulfide bondi1547 ↔ 1564PROSITE-ProRule annotation
Disulfide bondi1566 ↔ 1575PROSITE-ProRule annotation
Disulfide bondi1840 ↔ 1849PROSITE-ProRule annotation
Disulfide bondi1898 ↔ 1907PROSITE-ProRule annotation
Disulfide bondi1952 ↔ 1961PROSITE-ProRule annotation
Disulfide bondi1964 ↔ 1978PROSITE-ProRule annotation
Disulfide bondi2000 ↔ 2009PROSITE-ProRule annotation
Disulfide bondi2048 ↔ 2057PROSITE-ProRule annotation
Disulfide bondi2075 ↔ 2087PROSITE-ProRule annotation
Disulfide bondi2077 ↔ 2094PROSITE-ProRule annotation
Disulfide bondi2096 ↔ 2105PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

EPDiC1P641

Expressioni

Gene expression databases

BgeeiWBGene00001328
ExpressionAtlasiC1P641 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC1P641
SMRiC1P641
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 297Laminin N-terminalInterPro annotationAdd BLAST272
Domaini298 – 356Laminin EGF-likeInterPro annotationAdd BLAST59
Domaini357 – 426Laminin EGF-likeInterPro annotationAdd BLAST70
Domaini427 – 471Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini472 – 518Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini519 – 563Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini564 – 609Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini610 – 655Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini656 – 700Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini701 – 755Laminin EGF-likeInterPro annotationAdd BLAST55
Domaini756 – 808Laminin EGF-likeInterPro annotationAdd BLAST53
Domaini809 – 856Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1406 – 1451Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini1452 – 1496Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini1497 – 1544Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1545 – 1595Laminin EGF-likeInterPro annotationAdd BLAST51
Domaini1607 – 1787Laminin IV type AInterPro annotationAdd BLAST181
Domaini1821 – 1870Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini1871 – 1927Laminin EGF-likeInterPro annotationAdd BLAST57
Domaini1928 – 1980Laminin EGF-likeInterPro annotationAdd BLAST53
Domaini1981 – 2024Laminin EGF-likeInterPro annotationAdd BLAST44
Domaini2028 – 2074Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini2075 – 2122Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2684 – 2875LAM_G_DOMAINInterPro annotationAdd BLAST192
Domaini2887 – 3057LAM_G_DOMAINInterPro annotationAdd BLAST171
Domaini3063 – 3226LAM_G_DOMAINInterPro annotationAdd BLAST164
Domaini3301 – 3473LAM_G_DOMAINInterPro annotationAdd BLAST173
Domaini3479 – 3660LAM_G_DOMAINInterPro annotationAdd BLAST182

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili2298 – 2329Sequence analysisAdd BLAST32
Coiled coili2359 – 2379Sequence analysisAdd BLAST21
Coiled coili2408 – 2428Sequence analysisAdd BLAST21
Coiled coili2469 – 2496Sequence analysisAdd BLAST28
Coiled coili2527 – 2564Sequence analysisAdd BLAST38
Coiled coili2569 – 2614Sequence analysisAdd BLAST46

Keywords - Domaini

Coiled coilSequence analysis, Laminin EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IP6A Eukaryota
ENOG410ZVNS LUCA
GeneTreeiENSGT00780000121851
HOGENOMiHOG000017472

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR008979 Galactose-bd-like_sf
IPR010307 Laminin_dom_II
IPR002049 Laminin_EGF
IPR001791 Laminin_G
IPR000034 Laminin_IV
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
PfamiView protein in Pfam
PF00052 Laminin_B, 1 hit
PF00053 Laminin_EGF, 21 hits
PF00054 Laminin_G_1, 1 hit
PF02210 Laminin_G_2, 3 hits
PF06009 Laminin_II, 1 hit
PF00055 Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 14 hits
SM00180 EGF_Lam, 21 hits
SM00281 LamB, 1 hit
SM00282 LamG, 5 hits
SM00136 LamNT, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 6 hits
PROSITEiView protein in PROSITE
PS00022 EGF_1, 2 hits
PS01248 EGF_LAM_1, 6 hits
PS50027 EGF_LAM_2, 21 hits
PS50025 LAM_G_DOMAIN, 5 hits
PS51115 LAMININ_IVA, 1 hit
PS51117 LAMININ_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

C1P641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPYDSSPWA TKALFLIVTL LAQFTYSQVL TPSQITISHR KPITATSTCG
60 70 80 90 100
EIQGQPVTEI YCSLTGSTQY TPLNSYSYQD DEQQKSWSQY ENPMVRGGHG
110 120 130 140 150
CGHCNAGNEN SHPAANMVDG NNSWWMSPPL SRGLQHNEVN ITIDLEQEFH
160 170 180 190 200
VAYVWIQMAN SPRPGSWVLE RSTDHGKTYQ PWFNFAENAA ECMRRFGMES
210 220 230 240 250
LSPISEDDSV TCRTDMASLQ PLENAEMVIR ILEHRPSSRQ FATSEALQNF
260 270 280 290 300
TRATNVRLRL LGTRTLQGHL MDMNEWRDPT VTRRYFYAIK EIMIGGRCVC
310 320 330 340 350
NGHAVTCDIL EPQRPKSLLC RCEHNTCGDM CERCCPGFVQ KQWQAATAHN
360 370 380 390 400
NFTCEACNCF GRSNECEYDA EVDLNKQSID SQGNYEGGGV CKNCRENTEG
410 420 430 440 450
VNCNKCSFGY FRPEGVTWNE PQPCKVCDCD PDKHTGACAE ETGKCECLPR
460 470 480 490 500
FVGEDCDQCA SGYYDAPKCK PCECNVNGTI GDVCLPEDGQ CPCKAGFGGT
510 520 530 540 550
FCETCADGYT NVTAGCVECV CDATGSEHGN CSASTGQCEC KPAYAGLSCD
560 570 580 590 600
KCQVGYFGDD CKFCNCDPMG TEGGVCDQTT GQCLCKEGFA GDKCDRCDIA
610 620 630 640 650
FYGYPNCKAC ACDGAGITSP ECDATSGQCP CNGNFTGRTC DKCAAGFYNY
660 670 680 690 700
PDCRGCECLL SGAKGQTCDS NGQCYCKGNF EGERCDRCKP NFYNFPICEE
710 720 730 740 750
CNCNPSGVTR DFQGCDKVSP GELCSCRKHV TGRICDQCKP TFWDLQYHHE
760 770 780 790 800
DGCRSCDCNV NGTISGLNTC DLKTGQCMCK KNADGRRCDQ CADGFYRLNS
810 820 830 840 850
YNQMGCESCH CDIGGALRAE CDITSGQCKC RPRVTGLRCD QPIENHYFPT
860 870 880 890 900
LWHNQYEAED AHTEDQKPVR FAVDPEQFAD FSWRGYAVFS PIQDKILIDV
910 920 930 940 950
DITKATVYRL LFRYRNPTSV PVTATVTINP RFTHTHDVEQ TGKATFAPGD
960 970 980 990 1000
LPAMKEITVD GKPFVLNPGK WSLAISTKQR LFLDYVVVLP AEYYEGTVLR
1010 1020 1030 1040 1050
QRAPQPCLSH STKNTTCVDL IYPPIPSVSR QFVDMDKVPF NYINEDGTTT
1060 1070 1080 1090 1100
ALEHVPVEIL LSEITGPAAF VRADENPRVV EAKLDVPETG EYVIVLEYHN
1110 1120 1130 1140 1150
REETDGNIGV GISQNDKEVL NGNAVIHHCP YATFCRELVS SEGTIPYIPL
1160 1170 1180 1190 1200
EKGEATVRLN IKPNHEFGLA GVQLIKKSDF SSEYLQQVPV CIKKDARCVQ
1210 1220 1230 1240 1250
QSYPPAADSV TTEAESGSNM DKSILGDKLP FPVSNSKEMR VVPLDDAQAT
1260 1270 1280 1290 1300
VEISGVVPTR GHYMFMVHYF NPDNTPINID VLIQNEHYFQ ASVPLAFCPS
1310 1320 1330 1340 1350
ISGCRALIRD KERPEVIQFY MDDKYTATFY HNSSQKGPIY IDSITAVPYN
1360 1370 1380 1390 1400
SYKDKLMEPL ALDLSNEFLK ECSEDNLKNH PESVSDFCKQ KIFSLTTDFN
1410 1420 1430 1440 1450
AAALSCDCVA QGSESFQCEQ YGGQCKCKPG VIGRRCERCA PGYYNFPECI
1460 1470 1480 1490 1500
KCQCNAGQQC DERTGQCFCP PHVEGQTCDR CVSNAFGYDP LIGCQKCGCH
1510 1520 1530 1540 1550
PQGSEGGNLV CDPESGQCLC RESMGGRQCD RCLAGFYGFP HCYGCSCNRA
1560 1570 1580 1590 1600
GTTEEICDAT NAQCKCKENV YGGRCEACKA GTFDLSAENP LGCVNCFCFG
1610 1620 1630 1640 1650
VTDSCRSSMY PVTIMSVDMS SFLTTDDNGM VDNKDDTVIY TSEETSPNSV
1660 1670 1680 1690 1700
YFNVPIEKKD YTTSYGLKLT FKLSTVPRGG RKSMNADADV RLTGANMTIE
1710 1720 1730 1740 1750
YWASEQPTNP EEQFTVKCKL VPENFLTAEG KTVTREELMK VLHSLQNITL
1760 1770 1780 1790 1800
KASYFDHPKT STLYEFGLEI SEPNGVDSVI KASSVEQCQC PAPYTGPSCQ
1810 1820 1830 1840 1850
LCASGYHRVQ SGSFLGACVP CECNGHSATC DPDTGICTDC EHNTNGDHCE
1860 1870 1880 1890 1900
FCNEGHYGNA TNGSPYDCMA CACPFAPTNN FAKSCDVSEE GQLLQCNCKP
1910 1920 1930 1940 1950
GYTGDRCDRC ASGFFGHPQI SGESCSPCQC NGNNNLTDSR SCHPNSGDCY
1960 1970 1980 1990 2000
LCEQNTDGRH CESCAAWFYG DAVTAKNCSS CECSQCGSQY CDNKSGGCEC
2010 2020 2030 2040 2050
KINVEGDSCD RCKPDHWGFS KCQGCQGCHC GTAAFNTQCN VENGQCTCRP
2060 2070 2080 2090 2100
GATGMRCEHC EHGYWNYGEH GCDKCDCEAD LSMGTVCDVR TGQCHCQEGA
2110 2120 2130 2140 2150
TGSRCDQCLP SYLRIPTYGC RRCDECVHHL IGDVDNLELE IDVLGTAIAN
2160 2170 2180 2190 2200
ISSATIVGAR LARNKKEFND INEITKMLND EENSFGNVFG DAQDILTNST
2210 2220 2230 2240 2250
QIQNKLVRTK THSQNSVSSA KNITLNGTEF LQEVMKRAQR ARQSVRSLAE
2260 2270 2280 2290 2300
IALAIGSSSK AVNVDPRLLK EAEETLMTLE AASADQYPEK AQTVPGKLEE
2310 2320 2330 2340 2350
IQKKIQEETE KLDKQKETFE AQKKRAEELA AYLNSAQQLL KESKSKADKS
2360 2370 2380 2390 2400
NNIAKMLQLT KVENLVAAIT DDLERVEAAK GEFQKLNVAI GNITENLKDK
2410 2420 2430 2440 2450
REEMTHAVTT LNETRNDVAE ALEAAKKRVR RDEKSVDMQL VNAKAHELHL
2460 2470 2480 2490 2500
QATTLRQTFD NNKDNTDQAV EAANAFSNLT DTLKNAKAQI DNAYEALSAE
2510 2520 2530 2540 2550
PAFAESVQNA RDKPFPDETK EKIDALSKTV SQDLKETEKL KKQLEQLTEL
2560 2570 2580 2590 2600
SEKLRKRKEA VKAGIPKYSK NTLDSIDEKV QEVEKLKAEI DANIEETRAK
2610 2620 2630 2640 2650
ISEIAGKAEE ITEKANSAME GIRLARRNSV QLNKLAPVIV SKFEELKKLS
2660 2670 2680 2690 2700
SARSAKVDSV SDKVSQIKEM IAVARDAANR IKLGAHFEKG SSLDLNIPQR
2710 2720 2730 2740 2750
VTRSAAHADI SFYFRTEQEH GIPLFFGNEE TAVGSRAVPT ADYVAAEIEY
2760 2770 2780 2790 2800
GRPKITVDLG DAPAVVKLDT PVNDGLWRRL NIERIGKTVS VTLSKPNSVE
2810 2820 2830 2840 2850
TAETKSSVAG GNKSVLNLNQ QISRLFVGGV PTSARISKDL YNRDFVGDIE
2860 2870 2880 2890 2900
SLKLHGEPIG LWNSREKGNT NVNGAQKKPK ITDNADELVV SLDGEGYTSY
2910 2920 2930 2940 2950
KPSHWNPRKA TKISLSFLTF SPHGLLFFVG KDKDFMALEL SDGGVKLSVD
2960 2970 2980 2990 3000
LGSGVGQWIT ESSNYNDGKW HTVSIVREEK HVKIMIDGET EVLEGDVPGK
3010 3020 3030 3040 3050
DSEMSVTEFL YIGGTPSGLS VRTTIVPLRG CIKSVKLGSD NVDLESSHAS
3060 3070 3080 3090 3100
KGVRSGCPLH SVRTVSFLSD RTTASFNNAT EFSEDVSVTF KFKTRSIRQP
3110 3120 3130 3140 3150
SSLFTVNDDE DSVLSVSINE DGILTVTSGE DIATLELAAS PDEKWHYVSI
3160 3170 3180 3190 3200
RKTKYIIRID ADDSFSNEVA RKHADDSNPD ASFLSAFFGK SGETPSFVGC
3210 3220 3230 3240 3250
IGDVTLNGKL LDFANSEIKE ISLNGCSLSD DENISTTTTA APKPTDDSDV
3260 3270 3280 3290 3300
AVLPIDEEEE STTTTTTTTT EEPTEEPAEA RPDGHCSLPE DPMVQFEDAE
3310 3320 3330 3340 3350
GFNFGSQQYS RIEYDILPEA IDKSGEFTFK IRPTSDNGII FIATNKRTDH
3360 3370 3380 3390 3400
IAVMLEHGRV VFTYDTGSGQ VIIKSDKSII DGRWHTIKVS RRGKSAHLIV
3410 3420 3430 3440 3450
DDNSYESEGA ANQNEDLIET QPPFYVGGVP ADLAGFARNL VVGVRSQFSG
3460 3470 3480 3490 3500
CIKDFKLNGK SLDNGKEFGT EQCSQFSEPG MYFGKDGGYA IVQKDYEVGL
3510 3520 3530 3540 3550
TFGLEVEMRP RMKNGILFSV GVLEYITVEF VNGSIKTTVE SGSGGEELWH
3560 3570 3580 3590 3600
HPDIENQYCD GQWQSFKISK KRNLLTVAVN GKAHLKILKK AKTDVLTKDP
3610 3620 3630 3640 3650
LYFGGLPEGV TNKGIKTNKP FVGCIRFVSF GLKKDRKIRR KKQVDTERFD
3660
VFGDVHRNAC PAI
Length:3,663
Mass (Da):403,329
Last modified:May 26, 2009 - v1
Checksum:i63140F17256FAF66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAX65068.1
RefSeqiNP_001255501.1, NM_001268572.1
UniGeneiCel.18380

Genome annotation databases

EnsemblMetazoaiK08C7.3d; K08C7.3d; WBGene00001328
GeneIDi177956

Similar proteinsi

Entry informationi

Entry nameiC1P641_CAEEL
AccessioniPrimary (citable) accession number: C1P641
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: April 25, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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