C1KYE6 (PTH_LISMC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase
Short name=PTH
EC=3.1.1.29

Gene names

Name:	pth
Ordered Locus Names:	Lm4b_00211

Organism

Listeria monocytogenes serotype 4b (strain Clip81459) [Complete proteome] [HAMAP]

Taxonomic identifier

568819 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083
Subunit structure	Monomer By similarity. HAMAP MF_00083
Subcellular location	Cytoplasm By similarity HAMAP MF_00083.
Sequence similarities	Belongs to the PTH family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Peptidyl-tRNA hydrolase HAMAP MF_00083		PRO_1000202590

Sequences

	Sequence		Length	Mass (Da)
	C1KYE6 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 455FCEC408F66012	FASTA	186	21,002
	10 20 30 40 50 60 MKLIAGLGNP GKKYERTRHN VGFMVVDELS FRHQTPWKKS KFNGMTSEII VGGEKMILVK 70 80 90 100 110 120 PLTFMNASGE CIRPLMDYYN IPIEDVVIVY DDLDLPVGKI RLRQKGSAGG HNGMKSIIQH 130 140 150 160 170 180 VKTQEFNRIR VGVSRPLKGE VIHYVLGDFP KAEQPDIIAA IQKSADAIED FAQTPFIEVM NKYNQK

References

[1]	"Complete genome sequence of Listeria monocytogenes serotype 4b strain Clip81459." Rusniok C. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Clip81459.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM242711 Genomic DNA. Translation: CAS04001.1.
RefSeq	YP_002756949.1. NC_012488.1.
3D structure databases
ProteinModelPortal	C1KYE6.
ModBase	Search...
Protein-protein interaction databases
STRING	C1KYE6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7703646.
GenomeReviews	Gene locus Lm4b_00211 in contig FM242711_GR.
KEGG	lmc:Lm4b_00211.
PATRIC	20303532. VBILisMon88360_0217.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NTFMNNS.
ProtClustDB	PRK05426.
Family and domain databases
HAMAP	MF_00083. Pept_tRNA_hydro_bact. [Tree]
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KO	K01056.
PANTHER	PTHR17224. Pept_tRNA_hydro. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
SUPFAM	SSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMs	TIGR00447. Pth. 1 hit.
PROSITE	PS01195. PEPT_TRNA_HYDROL_1. 1 hit. PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PTH_LISMC

Accession

Primary (citable) accession number: C1KYE6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program