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C1KXG6 (C1KXG6_LISMC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Lm4b_02238
OrganismListeria monocytogenes serotype 4b (strain Clip81459) [Complete proteome] [HAMAP]
Taxonomic identifier568819 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1821Iron By similarity HAMAP MF_00323
Metal binding2631Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
C1KXG6 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 1AE5CC6331A45B85

FASTA30935,405
        10         20         30         40         50         60 
MTKKVGLLVM AYGTPYKDED IERYYTDIRH GHKPSEEMIA DLRGRYHAIG GLSPLAKITE 

        70         80         90        100        110        120 
AQAYGLEKAL NESQDEVEFK AYIGLKHIEP FIEDAVEAMH KDGIEEAISI VLAPHYSSFS 

       130        140        150        160        170        180 
VEAYNKRAKD AADKLGGLRI KAINDWYKQP KFIQMWADRI NETAKQIPAD ELLDTVLIVS 

       190        200        210        220        230        240 
AHSLPEKIKQ HNDPYPDQLQ ETADFIFEKV VVPHYALGWQ SEGKTGEPWL GPDVQDLTRE 

       250        260        270        280        290        300 
LYGREKYKHF IYTPVGFVAE HLEVLYDNDY ECKVVTDEVG ATYHRPPMPN SDPEFLEVLR 


TVVWEKYSN

« Hide

References

[1]"Complete genome sequence of Listeria monocytogenes serotype 4b strain Clip81459."
Rusniok C.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM242711 Genomic DNA. Translation: CAS05995.1.
RefSeqYP_002758926.1. NC_012488.1.

3D structure databases

ProteinModelPortalC1KXG6.
SMRC1KXG6. Positions 3-306.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1KXG6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7702862.
GenomeReviewsGene locus Lm4b_02238 in contig FM242711_GR.
PATRIC20307725. VBILisMon88360_2255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMASWYDEPK.
ProtClustDBPRK12435.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1KXG6_LISMC
AccessionPrimary (citable) accession number: C1KXG6
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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