C1KVS6 (TRPF_LISMC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	Lm4b_01640

Organism

Listeria monocytogenes serotype 4b (strain CLIP80459) [Complete proteome] [HAMAP]

Taxonomic identifier

568819 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Listeriaceae › Listeria › Listeria monocytogenes

Protein attributes

Sequence length	202 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 202	202	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000203209

Sequences

	Sequence		Length	Mass (Da)
	C1KVS6 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: C51837910D85CF45	FASTA	202	21,962
	10 20 30 40 50 60 MIVKICGLKK AVDVAAAVDN GADMIGFVFA KSKRQVTVEK AHELAKNIPA NVKKVGVFVN 70 80 90 100 110 120 PTEEELKAAI KGVPLDIVQL HGQEPAKQAN RTDAEVIKAF PVKDGKLPTN INDYPNAYIL 130 140 150 160 170 180 LDAPAEEYEG GSGKTFDWDK INRDMLTKNK LIIAGGLNAQ NVQEAIKRFE PYAVDISSGV 190 200 ETNGEKDPEK IKCFIKTAKG VE

References

[1]

"Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes." Hain T., Ghai R., Billion A., Kuenne C.T., Steinweg C., Izar B., Mohamed W., Mraheil M., Domann E., Schaffrath S., Karst U., Goesmann A., Oehm S., Puhler A., Merkl R., Vorwerk S., Glaser P., Garrido P. , Rusniok C., Buchrieser C., Goebel W., Chakraborty T. BMC Genomics 13:144-144(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIP80459.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM242711 Genomic DNA. Translation: CAS05401.1.
RefSeq	YP_002758337.1. NC_012488.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	634178.Lm4b_01640.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAS05401; CAS05401; Lm4b_01640.
GeneID	7701609.
KEGG	lmc:Lm4b_01640.
PATRIC	20306453. VBILisMon88360_1653.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000161598.
KO	K01817.
OMA	FVNASRC.
ProtClustDB	PRK01222.
Enzyme and pathway databases
BioCyc	LMON568819:GJF9-2425-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI_dom. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_LISMC

Accession

Primary (citable) accession number: C1KVS6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 26, 2009
Last modified:	May 29, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program