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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Listeria monocytogenes serotype 4b (strain CLIP80459)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciLMON568819:GJF9-2425-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:Lm4b_01640
OrganismiListeria monocytogenes serotype 4b (strain CLIP80459)
Taxonomic identifieri568819 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000002203: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 202202N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000203209Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi634178.Lm4b_01640.

Structurei

3D structure databases

ProteinModelPortaliC1KVS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

C1KVS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVKICGLKK AVDVAAAVDN GADMIGFVFA KSKRQVTVEK AHELAKNIPA
60 70 80 90 100
NVKKVGVFVN PTEEELKAAI KGVPLDIVQL HGQEPAKQAN RTDAEVIKAF
110 120 130 140 150
PVKDGKLPTN INDYPNAYIL LDAPAEEYEG GSGKTFDWDK INRDMLTKNK
160 170 180 190 200
LIIAGGLNAQ NVQEAIKRFE PYAVDISSGV ETNGEKDPEK IKCFIKTAKG

VE
Length:202
Mass (Da):21,962
Last modified:May 26, 2009 - v1
Checksum:iC51837910D85CF45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM242711 Genomic DNA. Translation: CAS05401.1.
RefSeqiYP_002758337.1. NC_012488.1.

Genome annotation databases

EnsemblBacteriaiCAS05401; CAS05401; Lm4b_01640.
GeneIDi7701609.
KEGGilmc:Lm4b_01640.
PATRICi20306453. VBILisMon88360_1653.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM242711 Genomic DNA. Translation: CAS05401.1.
RefSeqiYP_002758337.1. NC_012488.1.

3D structure databases

ProteinModelPortaliC1KVS6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634178.Lm4b_01640.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAS05401; CAS05401; Lm4b_01640.
GeneIDi7701609.
KEGGilmc:Lm4b_01640.
PATRICi20306453. VBILisMon88360_1653.

Phylogenomic databases

HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.
BioCyciLMON568819:GJF9-2425-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CLIP80459.

Entry informationi

Entry nameiTRPF_LISMC
AccessioniPrimary (citable) accession number: C1KVS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: February 4, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.