C1KVN6 (ARGB_LISMC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	Lm4b_01600

Organism

Listeria monocytogenes serotype 4b (strain Clip81459) [Complete proteome] [HAMAP]

Taxonomic identifier

568819 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 250	250	Acetylglutamate kinase HAMAP MF_00082_B		PRO_1000202565
Regions
	Region	41 – 42	2	Substrate binding By similarity
Sites
	Binding site	63	1	Substrate By similarity
	Binding site	156	1	Substrate By similarity
	Site	8	1	Transition state stabilizer By similarity
	Site	215	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	C1KVN6 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 5555F7F208DE3884	FASTA	250	26,550
	10 20 30 40 50 60 MENTIVVKLG GVASDNLTED FFQQIIQWQA ANKKIVLVHG GGHYITKMMK SLAIPVETKN 70 80 90 100 110 120 GLRVTNKATL EVTKMVLIGQ VQPAITTAFQ KRNISVIGLN AGDTGLLEAD FLNDANLGFV 130 140 150 160 170 180 GKITKVKTDL IEQLLSENII TVIAPLGINS EYDWLNVNAD TAACEVASAL QAEALYLLTD 190 200 210 220 230 240 VPGVKKGSEI IGEIATDEIE KLQYAGVIKG GMIPKLASAA FAAENGVGKV IITDSLNTSG 250 TKIKNKVAIG

References

[1]	"Complete genome sequence of Listeria monocytogenes serotype 4b strain Clip81459." Rusniok C. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Clip81459.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM242711 Genomic DNA. Translation: CAS05361.1.
RefSeq	YP_002758297.1. NC_012488.1.
3D structure databases
ProteinModelPortal	C1KVN6.
ModBase	Search...
Protein-protein interaction databases
STRING	C1KVN6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7704371.
GenomeReviews	Gene locus Lm4b_01600 in contig FM242711_GR.
KEGG	lmc:Lm4b_01600.
PATRIC	20306371. VBILisMon88360_1612.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GGNAMID.
ProtClustDB	PRK00942.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_LISMC

Accession

Primary (citable) accession number: C1KVN6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program