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Protein
Submitted name:

Bim alpha-1

Gene

BCL2L11

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SSC-111446. Activation of BIM and translocation to mitochondria.
R-SSC-111453. BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members.
R-SSC-193648. NRAGE signals death through JNK.

Names & Taxonomyi

Protein namesi
Submitted name:
Bim alpha-1Imported
Gene namesi
Name:BCL2L11Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiC1KGB6.

Expressioni

Gene expression databases

BgeeiENSSSCG00000022322.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000019550.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 39Bim_NInterPro annotationAdd BLAST36
Domaini128 – 164Bclx_interactInterPro annotationAdd BLAST37

Phylogenomic databases

eggNOGiENOG410IZKS. Eukaryota.
ENOG410Y8GB. LUCA.
GeneTreeiENSGT00390000003178.
HOGENOMiHOG000231637.
OrthoDBiEOG091G0XD3.
TreeFamiTF335898.

Family and domain databases

InterProiView protein in InterPro
IPR014771. Apoptosis_Bim_N.
IPR015040. Bcl-x_interacting_BH3_dom.
PfamiView protein in Pfam
PF08945. Bclx_interact. 1 hit.
PF06773. Bim_N. 1 hit.

Sequencei

Sequence statusi: Complete.

C1KGB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKQPSDVSS ECDREGGQLQ PAERPPQLRP GAPTSLQTER QGNPEGEGDR
60 70 80 90 100
CPQGSPQGPL APPTSPGPFA TRSPLFIFVR RSSLLSRSSS GYFSFDTDRS
110 120 130 140 150
PAPMSCDKST QTPSPPCQAF NHYLSAMASM RQSQAEPADM RPEIWIAQEL
160 170 180
RRIGDEFNAY YPRRVMLFSL PPFSPHTLPP PYI
Length:183
Mass (Da):20,195
Last modified:May 26, 2009 - v1
Checksum:i2613F428BB422F75
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000020 Genomic DNA. No translation available.
FJ825619 mRNA. Translation: ACO55050.1.
RefSeqiNP_001239123.1. NM_001252194.1.
UniGeneiSsc.23493.
Ssc.99589.

Genome annotation databases

EnsembliENSSSCT00000023378; ENSSSCP00000019550; ENSSSCG00000022322.
GeneIDi396632.

Similar proteinsi

Entry informationi

Entry nameiC1KGB6_PIG
AccessioniPrimary (citable) accession number: C1KGB6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: January 31, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported