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C1H8X1

- C1H8X1_PARBA

UniProt

C1H8X1 - C1H8X1_PARBA

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Protein

DNA ligase

Gene

PAAG_07212

Organism
Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PAAG_07212Imported
OrganismiParacoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)Imported
Taxonomic identifieri502779 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesParacoccidioides
ProteomesiUP000002059: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1H8X1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPIPAKKRKL NEPGPANQRT RGIESFFRSQ KSASATITPV QLEPGTPLAD
60 70 80 90 100
EALARKLQAK WDEEAKSGNQ CSSNLQGYQH PSTLETKPEG LTQEFGTRLQ
110 120 130 140 150
THGTSVCGDV SGNGKPNRVL SLQISSSAED TISQSIPFDQ SPLTFEPSSY
160 170 180 190 200
AENLRAHWAL EGGHASYAIL TRAFVLVNNT QSRIKIVDTL VNLLRLLIEA
210 220 230 240 250
DPDSLIFAVW LATNAIAPPY VPVELGLGGS AISKALKTAY GLNNQGLKTL
260 270 280 290 300
WDKYGDAGDV AFEAKKRQTF TLRKPKPLSI RGVYESLLKI SRSKGPGSQE
310 320 330 340 350
IKQRIVEKLL QDARGAEESR YIVRTLVQHL RIGAVKTTML IALARAFLYS
360 370 380 390 400
RPSTKDFFVN NRTELSKLKR EEMASIYSRA EEIVKASYAR HPSYDDLVSC
410 420 430 440 450
LLEIGISDEL LVRCGLTLHV PLHPMLGSIT RDLAQMLTKL QGRAFTCEYK
460 470 480 490 500
YDGQRAQVHC DSSGKVSIFS RHLELMTDKY PDLVALIPRI RGEGVSSFIL
510 520 530 540 550
EGEIVAVNQE TGELLAFQTL TNRAKKNVGI ESIEISVCLF AFDLMLLNGE
560 570 580 590 600
PLLERPLRER RELLRGLFIE VPHHFTWVKN LDATSSDSEA VLSFFKEAID
610 620 630 640 650
AKCEGLMVKL LDDSVQPELS KYESVAEPNL NSDLLLTTGP VEPNGNNKTR
660 670 680 690 700
ARRSLLSTYE PDKRLESWLK VKKDYNAASD TLDLIPIAAW HGQGRKAKWW
710 720 730 740 750
SPILLAVRNP ETGMLEAVTK CISGFTDKFY QANKEKYAEG SDNIISRPSY
760 770 780 790 800
VDYRSEPEVW FEPQEVWEVA FADITLSPTY TAAIGLVSDE RGLSLRFPRF
810 820 830 840 850
VRVREDKGLE EASSSDYLAN LWRKQTERLQ EEGAIAKPIT ESNHFGSEDD
Length:850
Mass (Da):94,872
Last modified:May 26, 2009 - v1
Checksum:iE7F4DC9356DA5CD7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS572832 Genomic DNA. Translation: EEH36794.1.
RefSeqiXP_002790976.1. XM_002790930.1.

Genome annotation databases

GeneIDi9094153.
KEGGipbl:PAAG_07212.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS572832 Genomic DNA. Translation: EEH36794.1 .
RefSeqi XP_002790976.1. XM_002790930.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9094153.
KEGGi pbl:PAAG_07212.

Phylogenomic databases

KOi K10747.
OrthoDBi EOG7TXKRG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-826 / Pb01Imported.

Entry informationi

Entry nameiC1H8X1_PARBA
AccessioniPrimary (citable) accession number: C1H8X1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3