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Protein

Glutamate decarboxylase

Gene

PAAG_04483

Organism
Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:PAAG_04483Imported
OrganismiParacoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)Imported
Taxonomic identifieri502779 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesOnygenales incertae sedisParacoccidioides
Proteomesi
  • UP000002059 Componenti: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:PAAG_04483

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei302N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi502779.XP_002793573.1

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili401 – 421Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1383 Eukaryota
COG0076 LUCA
KOiK01580
OrthoDBiEOG092C1P0W

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 2 hits
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

C1H139-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLACHVDAN KLVEELRSDP ERRKSERLWT ESVSGSMIPY PTRYASREEI
60 70 80 90 100
PRFKIPKEGA PAEAVRRMLR DHLDLDGIPN LNMASFVGTY MEREADELLS
110 120 130 140 150
ENINKNLADA DEYPALMEMH AHCVSMLANL WNAQPGGNAI GSATTGSSEA
160 170 180 190 200
IHLGGLAMKR RWQEKRRAAG KDISKPNIIM GANAQVALLK FARYFEVEPR
210 220 230 240 250
ILDVSEKSQY RLDPELVKKN VDENTLGVFV ILGSTYTGHY EPVEEISNIL
260 270 280 290 300
DEYQAKTGED VPIHVDAASG GFVAPFAFAQ AGGSKWDFLL PRVKSINTSG
310 320 330 340 350
HKFGLVYAGL GWIIWRDRSY LPKDLIFELH YLGGTEETFT LNFSRPGMQV
360 370 380 390 400
IGQYYNFIRL GFNGYREIME NCLANARLLS KALEKTGWFV CVSDIHRKKG
410 420 430 440 450
NFNLGQTAEE LKELLKNVEG ETSADYNAGL PVVAFRLSDV FQKKYPDVKQ
460 470 480 490 500
DSISLLLRAK QYIIPNYPLP PAVDKTEILR IVVRESMSAD LIDRLVADTV
510 520 530 540 550
AITEKLMEKP VDIAALHTGS TSIARRHMAA NGERGAKGTR KHHPDGIHRS

VC
Length:552
Mass (Da):61,741
Last modified:May 26, 2009 - v1
Checksum:i04B5413F734F4828
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN294002 Genomic DNA Translation: EEH33433.1
RefSeqiXP_002793573.1, XM_002793527.1

Genome annotation databases

EnsemblFungiiEEH33433; EEH33433; PAAG_04483
GeneIDi9096738
KEGGipbl:PAAG_04483

Similar proteinsi

Entry informationi

Entry nameiC1H139_PARBA
AccessioniPrimary (citable) accession number: C1H139
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: April 25, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health