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Protein

Histone-lysine N-methyltransferase

Gene

PAAG_03011

Organism
Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
ORF Names:PAAG_03011Imported
OrganismiParacoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)Imported
Taxonomic identifieri502779 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesParacoccidioides
ProteomesiUP000002059: Partially assembled WGS

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation

Phylogenomic databases

KOiK11419.
OrthoDBiEOG7MD509.

Family and domain databases

InterProiIPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1GY57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVIDLTRDSS SEDDPRHGVE PEIRTPPHDE GLTLLQKFTR PSLRPGSSSS
60 70 80 90 100
GGTMRNEWKS TASTNGAISS TLNGVLPSNK PPQPSFAVVV PSLGCDTGIK
110 120 130 140 150
RRRLSSEDDS SSQANGVDPE FPNHHGLSSF YSVERRSKAL TYQPKQEVSR
160 170 180 190 200
NRANIQIKQP AVRYHPFQKG HSDKDILSLY LKKLQRIQGP PVTLKIDPSD
210 220 230 240 250
ASNIDFNFEF INEYKLQKGV KRVDPGFHVG CQCVGVCDSS SCYHLDRLPN
260 270 280 290 300
EDEDEDEVSE HQIIPYQVGR DGKVVLRHEF FRKRAMIYEC SPLCTCLPSC
310 320 330 340 350
LNRVVQKGRT LKLEIFRTDN RGFGLRSPEN IQAGQYIDRY LGEVITRKEA
360 370 380 390 400
DAREAATPKN SASYLFQLDF FISAEENCYI VDGRKYGSIT RFMNHSCRPN
410 420 430 440 450
CRMFPVSQYE AERNIFDMAF FAIKNIPAGT ELTFDYCPYS DKEGSKAVDP
460 470
DAVKCLCGER TCRGQLWPNQ RKTM
Length:474
Mass (Da):53,549
Last modified:February 4, 2015 - v2
Checksum:iD2E6D58F156CB5A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN293999 Genomic DNA. Translation: EEH41448.2.

Genome annotation databases

KEGGipbl:PAAG_03011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN293999 Genomic DNA. Translation: EEH41448.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGipbl:PAAG_03011.

Phylogenomic databases

KOiK11419.
OrthoDBiEOG7MD509.

Family and domain databases

InterProiIPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-826 / Pb01Imported.

Entry informationi

Entry nameiC1GY57_PARBA
AccessioniPrimary (citable) accession number: C1GY57
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: February 4, 2015
Last modified: March 4, 2015
This is version 37 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.