C1G0G7 (C1G0G7_PARBD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphatidylinositol 3-kinase tor2 EMBL EEH44068.1

Gene names

ORF Names:

PADG_00357 EMBL EEH44068.1

Organism

Paracoccidioides brasiliensis (strain Pb18) [Complete proteome] EMBL EEH44068.1

Taxonomic identifier

502780 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Onygenales › mitosporic Onygenales › Paracoccidioides › Paracoccidioides brasiliensis

Protein attributes

Sequence length	2374 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 FAT domain. SAAS SAAS018936 Contains 1 FATC domain. SAAS SAAS018936 Contains 1 PI3K/PI4K domain.

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS003152 Nucleotide-binding
Molecular function	Kinase SAAS SAAS018936 EMBL EEH44068.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW drug binding Inferred from electronic annotation. Source: InterPro kinase activity Inferred from electronic annotation. Source: UniProtKB-KW phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1G0G7 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: C9D4D05105E8BA2B	FASTA	2,374	268,138
	10 20 30 40 50 60 MAQVPSGTDA TQRIFHDLKS KHEETRSRAS FELHENVAVA SRELPPDKFI EYYNAVSQRI 70 80 90 100 110 120 AQLVVTGNDV NEKIGGLLAL DRLIDFDGVD AAQKTTRFAS YLRSALRSND STVLVYAARS 130 140 150 160 170 180 LGRLAKPGGA LTAELVESEI QSAMEWLQSE RQENRRFAAV LVIRELAKGS PTLLYGFVPQ 190 200 210 220 230 240 IFELIWVALR DQKVLIRETS AQAVSECFEI LAARDFQVRQ QWFGRIYEEC LLGLRSSNVD 250 260 270 280 290 300 WIHGSLLTLR ELLLKGAMFM NEHYRNACEI VLRLKDHREP KIRIQIVLTI PILASYAPLE 310 320 330 340 350 360 FTNIYLHRFM IYLQAQLKRE KERNAAFIAI GKIANAVGNS IAQFLDGIIV YIREGLTLKA 370 380 390 400 410 420 RNRAAVDEGP MFECISMLSL AVGQTLSKYM EALLDPIFAC GLSESLTQAL VDMAHYIPPI 430 440 450 460 470 480 KATIQEKLLD MLSIVLCGTP FRPLGCPENR PPPMPSFAKD YGPFLQEPTD NEIALALHTL 490 500 510 520 530 540 GSFDFSGHIL NEFVRDVAIT FVNNDNPEIR KASALTCCQL FVSDPILNQK SSHSIQVVGE 550 560 570 580 590 600 VVDTLLTVGI GDPDPDIRRI VLESLDKKFD SHLAKPESVR CLFLAVNDEV FPVREAAISI 610 620 630 640 650 660 IGRLSGVNPA YVFPPLRKLL VNLLTGLSFA TTSRQKEESA QLISLFVANA TKLVRSYVDP 670 680 690 700 710 720 MVTALFPKTT DPNPGVAATT LKAIGELATV GGEDMRQYLP QLMPIILDAL QDLSCQSKRE 730 740 750 760 770 780 AALRTLGQLA SNAGYVIEPY LEYPHLLAVL INIVKTEQTG SLRKETIKLL GIIGALDPYK 790 800 810 820 830 840 HQQISESVPD IHHINEVQRV SDVSLIMQGL TPSNEEYYPT IVINTLLQNI LNESSLAQYH 850 860 870 880 890 900 SAVIDAIVTI FKTLGLKCVP FLGQIIPAFV LVIRSTPTSR LESYFNQLAI LVTIVRQHIR 910 920 930 940 950 960 AFLPEIIEVI REFWDSSYQV QATILSLIEA IAKSLEGEFK KYLAGLIPLM LDTLDKDITP 970 980 990 1000 1010 1020 RRQPSERILH TFLIFGSSGE EYMHLIAPAI VRLFDKTQSP SGIRKSAIET LGKLSRQVNV 1030 1040 1050 1060 1070 1080 SDFSSLMIHP LSRVIAGTDR TLRQAALDCI CTLIFQLGQD FNNYIQLINK TISAHQISHH 1090 1100 1110 1120 1130 1140 NYQILVSKLQ KGDPLPQDLN PDEHYSTLGD DSTFADVGQK KILVNQQHLK NAWDASQKST 1150 1160 1170 1180 1190 1200 REDWQEWIRR FSVELLKESP SHALRACASL AGIYQPLAKD LFNAAFVSCW TELYGQYQEE 1210 1220 1230 1240 1250 1260 LVRSIDMALT SQNIPPEILQ ILLNLAEFME HDDKALHIDI RTLGKYAGKC HAFAKALHYK 1270 1280 1290 1300 1310 1320 ELEFEQDQNS GAVEALISIN NQLQQSDAAI GILRKAQAYR DVELKETWFV KLQRWEEALA 1330 1340 1350 1360 1370 1380 AYKRRELIDP DSFDVTMGKM RCLHALGEWK MLSDLAQEKW NHASNEHRKA MAPLAAGAAW 1390 1400 1410 1420 1430 1440 GRGQWELMDS YISVMKEQTP DRSFFGAILA IHNRKFDEAA MFIEKARNGL DTELSALLGE 1450 1460 1470 1480 1490 1500 SYNRAYNVVV RVQMLAELEE IIIYKQSDDD PEKQEAMKET WNKRLLGCQQ NVEVWQRMLK 1510 1520 1530 1540 1550 1560 VRALVISPRE NLDMWIKFAN LCRKSNRMGL ADRSLSSLEG GELGTPPEVA YARLKYEWAA 1570 1580 1590 1600 1610 1620 GRQKEALQML RDFTIGLTEE FARYNAALVA HSEHAPADRP GLVNGISDHP ELALTRQHIG 1630 1640 1650 1660 1670 1680 DVGKFRRLLA KSHLKQGEWQ TALQRGDWTS EGVRDVLNSY SAATQYNRDS YKAWHAWALA 1690 1700 1710 1720 1730 1740 NFEVVNALST QTNRETVVPH HIVLEHVIPA IRGFFRSIAL SSTSSLQDTL RLLTLWFTHG 1750 1760 1770 1780 1790 1800 GDAEVSGVVS EGFTSVIVDT WLEVTPQLIA RINQPNARVR GAVHRLLAEV GKAHPQALVY 1810 1820 1830 1840 1850 1860 PLTVATMSNV VRRSQSASHI MDSMRQHSPR LVEQAEIVSH ELIRVAVLWH ELWHEGLEEA 1870 1880 1890 1900 1910 1920 SRLYFGDHNV EGMFATLAPL HDMLDKGAET LREVSFAQAF GRDLAEAKHF CLLYRESGVI 1930 1940 1950 1960 1970 1980 GDLNQAWDLY YTVFRKIARQ LPQLQSLDLK YVSPKLKDAV DLELAVPGTY QSGKPVIRIM 1990 2000 2010 2020 2030 2040 SFDPVSIVLQ TKKRPRKMTL KGSDGNSYMY ALKGHEDIRQ DERVMQLFGL VNTLLDHDSE 2050 2060 2070 2080 2090 2100 SFKRHLTIQR FPAIPLSQNS GLIGWVSNTD TLHALIKEYR ESRRILLNIE HRIMLQMAPD 2110 2120 2130 2140 2150 2160 YDNLTLMQKV EVFGYAMDNT TGKDLYRVLW LKSKSSESWL ERRTNYTRSL GVMSMVGYIL 2170 2180 2190 2200 2210 2220 GLGDRHPSNL LLERITGKIV HIDFGDCFEI AMHREKYPER VPFRLTRMLT FAMEVSNIEG 2230 2240 2250 2260 2270 2280 SYHITCEAVM RVIRENKESL MAVLEAFIHD PLINWRLGAR ESPARPSFAA DRRQSVVEEI 2290 2300 2310 2320 2330 2340 NMDHPMQPSN FSRRRPSILE GGILDAQQGV PNEAREVQNA RALQVLSRVK EKLTGRDFKS 2350 2360 2370 TEELNVSDQV DKLLVQATSV ENLCQHYIGW CSFW

References

[1]

"Annotation of Paracoccidioides brasiliensis Pb18." McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Ma L.-J.J., Henn M.R., Champion M., Cuomo C., Jaffe D.B., Young S.K., Gnerre S., Berlin A., Heiman D., Hepburn T., Sykes S., Yandava C., Alvarado L., Kodira C.D. , Guigo R., Borodovsky M., Goldman B., Klein B., Mendoza L., Nino-Vega G., San-Blas G., Sil A., de Almeida Soares C.M., Taylor J., Lander E.S., Nusbaum C., Galagan J.E., Birren B.W. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Pb18.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS572750 Genomic DNA. Translation: EEH44068.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.1070.11. 3 hits. 1.25.10.10. 6 hits.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR024585. DUF3385_TOR. IPR003152. FATC. IPR021133. HEAT_type_2. IPR011009. Kinase-like_dom. IPR000403. PI3/4_kinase_cat_dom. IPR018936. PI3/4_kinase_CS. IPR003151. PIK-rel_kinase_FAT. IPR014009. PIK_FAT. IPR009076. Rapamycin-bd_dom. IPR026683. TOR/Smg1. [Graphical view]
PANTHER	PTHR11139:SF9. PTHR11139:SF9. 1 hit.
Pfam	PF11865. DUF3385. 1 hit. PF02259. FAT. 1 hit. PF02260. FATC. 1 hit. PF00454. PI3_PI4_kinase. 1 hit. PF08771. Rapamycin_bind. 1 hit. [Graphical view]
SMART	SM00146. PI3Kc. 1 hit. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit. SSF47212. FRAP_FKBP12_bind. 1 hit. SSF56112. Kinase_like. 1 hit.
PROSITE	PS51189. FAT. 1 hit. PS51190. FATC. 1 hit. PS50077. HEAT_REPEAT. 1 hit. PS00915. PI3_4_KINASE_1. 1 hit. PS50290. PI3_4_KINASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1G0G7_PARBD

Accession

Primary (citable) accession number: C1G0G7

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	March 6, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)