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C1FS47 (C1FS47_CLOBJ) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal protein S12 methylthiotransferase RimO HAMAP-Rule MF_01865

Short name=S12 MTTase HAMAP-Rule MF_01865
Short name=S12 methylthiotransferase HAMAP-Rule MF_01865
EC=2.-.-.- HAMAP-Rule MF_01865
Alternative name(s):
Ribosome maturation factor RimO HAMAP-Rule MF_01865
methylthiotransferase HAMAP-Rule MF_01865
Gene names
Name:rimO HAMAP-Rule MF_01865
Ordered Locus Names:CLM_2699 EMBL ACO86397.1
OrganismClostridium botulinum (strain Kyoto / Type A2) [Complete proteome] [HAMAP] EMBL ACO86397.1
Taxonomic identifier536232 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 By similarity. HAMAP-Rule MF_01865

Cofactor

Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity. HAMAP-Rule MF_01865

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01865 SAAS SAAS005840.

Sequence similarities

Belongs to the methylthiotransferase family. RimO subfamily. HAMAP-Rule MF_01865

Contains 1 MTTase N-terminal domain. HAMAP-Rule MF_01865

Contains 1 TRAM domain. HAMAP-Rule MF_01865

Contains MTTase N-terminal domain. SAAS SAAS005840

Contains TRAM domain. SAAS SAAS005840

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain4 – 119116MTTase N-terminal By similarity HAMAP-Rule MF_01865
Domain375 – 44167TRAM By similarity HAMAP-Rule MF_01865

Sites

Metal binding131Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01865
Metal binding481Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01865
Metal binding821Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01865
Metal binding1561Iron-sulfur (4Fe-4S-S-AdoMet) By similarity HAMAP-Rule MF_01865
Metal binding1601Iron-sulfur (4Fe-4S-S-AdoMet) By similarity HAMAP-Rule MF_01865
Metal binding1631Iron-sulfur (4Fe-4S-S-AdoMet) By similarity HAMAP-Rule MF_01865

Sequences

Sequence LengthMass (Da)Tools
C1FS47 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: F3A5018A43591715

FASTA44551,361
        10         20         30         40         50         60 
MEKIKVALVS LGCDKNRIDS ELMLYKLNEE AELVKNPKEA QVIIVNTCGF IETAKEESIN 

        70         80         90        100        110        120 
TILQMASYKK THNCKVLVVT GCLTQRYKGE LKELIPEMDI MLGVNDYDKL LESIKVFLKS 

       130        140        150        160        170        180 
GEKSFYHKYS DTKINEGNRI LTTPTYTAYV RIAEGCNNFC TYCAIPRIRG KYRSRKKENI 

       190        200        210        220        230        240 
LKEVENLAKQ GVKEIILIAQ DTTMYGIDIY GKKVLHELLR DISKVEGVKW IRLLYCYPEE 

       250        260        270        280        290        300 
ITKELIEEIK NNDKVCKYLD LPIQQISNSV LKRMGRKTTK ETIINIIKKL RKEIEGITLR 

       310        320        330        340        350        360 
TSLIVGFPGE TEGEFSELKE FVSDVKLDKL GVFKYSKEEG TSAALMKEQI DEEIKEKREE 

       370        380        390        400        410        420 
EIMILQQSIS KDINKEKIGK IYEVIVEGTK EDMYYGRNYE MSPEIDGEIY FEKDENVKIG 

       430        440 
DIIKVKVTHS LEYDLIGVVY NELSK 

« Hide

References

[1]"Genome sequence of Clostridium botulinum A2 Kyoto."
Shrivastava S., Brinkac L.M., Brown J.L., Bruce D., Detter C.C., Johnson E.A., Munk C.A., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Kyoto / Type A2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001581 Genomic DNA. Translation: ACO86397.1.
RefSeqYP_002804850.1. NC_012563.1.

3D structure databases

ProteinModelPortalC1FS47.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING536232.CLM_2699.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACO86397; ACO86397; CLM_2699.
GeneID7765153.
KEGGcby:CLM_2699.
PATRIC19381855. VBICloBot91161_2553.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0621.
HOGENOMHOG000224766.
KOK14441.
OMACLMQRYR.
OrthoDBEOG6P5ZD8.
ProtClustDBCLSK882944.

Enzyme and pathway databases

BioCycCBOT536232:GCO3-2619-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
3.80.30.20. 1 hit.
HAMAPMF_01865. MTTase_RimO.
InterProIPR006638. Elp3/MiaB/NifB.
IPR023970. MeThioTfrase/rSAM.
IPR005839. Methylthiotransferase.
IPR020612. Methylthiotransferase_CS.
IPR013848. Methylthiotransferase_N.
IPR012340. NA-bd_OB-fold.
IPR005840. Ribosomal_S12_MeSTrfase_RimO.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
IPR002792. TRAM_dom.
[Graphical view]
PANTHERPTHR11918. PTHR11918. 1 hit.
PfamPF04055. Radical_SAM. 1 hit.
PF00919. UPF0004. 1 hit.
[Graphical view]
SMARTSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00089. TIGR00089. 1 hit.
TIGR01125. TIGR01125. 1 hit.
PROSITEPS51449. MTTASE_N. 1 hit.
PS01278. MTTASE_RADICAL. 1 hit.
PS50926. TRAM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1FS47_CLOBJ
AccessionPrimary (citable) accession number: C1FS47
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)