Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C1FQW3

- PGK_CLOBJ

UniProt

C1FQW3 - PGK_CLOBJ

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Clostridium botulinum (strain Kyoto / Type A2)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei38 – 381SubstrateUniRule annotation
    Binding sitei122 – 1221SubstrateUniRule annotation
    Binding sitei155 – 1551SubstrateUniRule annotation
    Binding sitei206 – 2061ATPUniRule annotation
    Binding sitei297 – 2971ATP; via carbonyl oxygenUniRule annotation
    Binding sitei328 – 3281ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi354 – 3574ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCBOT536232:GCO3-263-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:CLM_0277
    OrganismiClostridium botulinum (strain Kyoto / Type A2)
    Taxonomic identifieri536232 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000001374: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 398398Phosphoglycerate kinasePRO_1000192817Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi536232.CLM_0277.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni23 – 253Substrate bindingUniRule annotation
    Regioni61 – 644Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227108.
    KOiK00927.
    OMAiWEALDIG.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C1FQW3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNYNKKSIEY IDVKGKKVLV RCDFNVPLNE GKITDENRLV GALPTIKYLM    50
    EKGAKIILCS HMGKPKGEPK KELSLLPVAK RLSEMLNKEV IFADDDNVVG 100
    ENAKKAVEDM KDGDVVLLQN TRYRKEETKN EEVFSKELAS LADVFVNDAF 150
    GTAHRAHCST VGVTNYLKEA ACGYLIQKEL KFLGNAVEKP ERPFVAILGG 200
    AKVSDKINVI NNLLDKVDTL IIGGGMGYTF LKAQGYTIGN SLVEEDKVEY 250
    SKEMIDKAKE KGVNLLLPID NVVADKFDKD ASPVVTEDQN IGEGYMGLDI 300
    GPKTAKIYSD AIKSAKTVVW NGPMGVFEFK SFANGTIEVA KAMADSDAVT 350
    IIGGGDSAAA VNILGFGDKM THISTGGGAS LEFLEGKELP GIAALNDK 398
    Length:398
    Mass (Da):43,097
    Last modified:May 26, 2009 - v1
    Checksum:i94F9F6D8943F06BD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001581 Genomic DNA. Translation: ACO85178.1.
    RefSeqiYP_002802539.1. NC_012563.1.

    Genome annotation databases

    EnsemblBacteriaiACO85178; ACO85178; CLM_0277.
    GeneIDi7766208.
    KEGGicby:CLM_0277.
    PATRICi19377173. VBICloBot91161_0219.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001581 Genomic DNA. Translation: ACO85178.1 .
    RefSeqi YP_002802539.1. NC_012563.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 536232.CLM_0277.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO85178 ; ACO85178 ; CLM_0277 .
    GeneIDi 7766208.
    KEGGi cby:CLM_0277.
    PATRICi 19377173. VBICloBot91161_0219.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227108.
    KOi K00927.
    OMAi WEALDIG.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci CBOT536232:GCO3-263-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Clostridium botulinum A2 Kyoto."
      Shrivastava S., Brinkac L.M., Brown J.L., Bruce D., Detter C.C., Johnson E.A., Munk C.A., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Kyoto / Type A2.

    Entry informationi

    Entry nameiPGK_CLOBJ
    AccessioniPrimary (citable) accession number: C1FQW3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3