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C1FLB3 (PYRF_CLOBJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:CLM_3650
OrganismClostridium botulinum (strain Kyoto / Type A2) [Complete proteome] [HAMAP]
Taxonomic identifier536232 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 283283Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000164745

Sites

Active site971Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
C1FLB3 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: D111BDF8145B8706

FASTA28331,961
        10         20         30         40         50         60 
MIIDKLYENV EKKGCVCVGL DTDISYLPKG FLNKFTNIED AIFAFNQRIV DSTFDVSACY 

        70         80         90        100        110        120 
KVQIAYYEAM GIKGMILYKK TLEYIRKKGG IVIADIKRGD ISATAKMYAK AHFEGDFESD 

       130        140        150        160        170        180 
FITLNPYMGM DTLEPYKDYF KNKEKGVFLL LRTSNEGSKD IQYLDLKDNK KVYNKVGEKI 

       190        200        210        220        230        240 
ENIGKEFLGN CRYSSIGAVV GCTAEENNIR KELKHTFFLI PGYGAQGGKA EVAKYYLSGG 

       250        260        270        280 
NGGIVNSSRG ILLAYKKYDE EGKNFEECAR NEVINMKKTL QII 

« Hide

References

[1]"Genome sequence of Clostridium botulinum A2 Kyoto."
Shrivastava S., Brinkac L.M., Brown J.L., Bruce D., Detter C.C., Johnson E.A., Munk C.A., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Kyoto / Type A2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001581 Genomic DNA. Translation: ACO83525.1.
RefSeqYP_002805757.1. NC_012563.1.

3D structure databases

ProteinModelPortalC1FLB3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING536232.CLM_3650.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACO83525; ACO83525; CLM_3650.
GeneID7767178.
KEGGcby:CLM_3650.
PATRIC19383707. VBICloBot91161_3471.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245747.
KOK01591.
OMACDILLTA.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycCBOT536232:GCO3-3546-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
ProtoNetSearch...

Entry information

Entry namePYRF_CLOBJ
AccessionPrimary (citable) accession number: C1FLB3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways