C1FAE6 (C1FAE6_ACIC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
EC=2.5.1.55 HAMAP MF_00056

Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase HAMAP MF_00056
KDO-8-phosphate synthase HAMAP MF_00056
Phospho-2-dehydro-3-deoxyoctonate aldolase HAMAP MF_00056

Gene names

Name:	kdsA HAMAP MF_00056 EMBL ACO31549.1
Ordered Locus Names:	ACP_2344

Organism

Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]

Taxonomic identifier

240015 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056 SAAS SAAS006269
Pathway	Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056 SAAS SAAS006269 Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056 SAAS SAAS006269
Subcellular location	Cytoplasm By similarity HAMAP MF_00056 SAAS SAAS006269.
Sequence similarities	Belongs to the KdsA family. HAMAP MF_00056

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis HAMAP MF_00056 SAAS SAAS006269
Cellular component	Cytoplasm HAMAP MF_00056 SAAS SAAS006269
Molecular function	Transferase HAMAP MF_00056 SAAS SAAS006269 EMBL ACO31549.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-deoxy-8-phosphooctulonate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1FAE6 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 42853340B3DD640D	FASTA	294	31,065
	10 20 30 40 50 60 MGGFASRSGS TCVRSRACDS IQAVNQPFSI GPVPVGSGQL FLIAGPCVIE SEAHARKMAD 70 80 90 100 110 120 AIQRITADLG VPYIFKASYD KANRTSVTSF RGPGLVEGTR ILKTIQQQHG LPVLTDVHEP 130 140 150 160 170 180 GHCAVAAEGV DVLQIPAFLC RQTDLLVAAA NTGRAVNVKK GQFVAPWDMQ HAVGKLESTG 190 200 210 220 230 240 NPRFFLTERG ASFGYNNLVV DMRSLGIMRK MAPVVFDGTH SVQIPSGSNG VSGGQPEFIP 250 260 270 280 290 LLTRAAVAAG VDGLFLEVHD NPAEAKSDGA NALHLDRLRP LLENLLAIHA AAHG

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001472 Genomic DNA. Translation: ACO31549.1.
RefSeq	YP_002755388.1. NC_012483.1.
3D structure databases
ProteinModelPortal	C1FAE6.
ModBase	Search...
Protein-protein interaction databases
STRING	C1FAE6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7698737.
GenomeReviews	Gene locus ACP_2344 in contig CP001472_GR.
KEGG	aca:ACP_2344.
PATRIC	20667945. VBIAciCap40988_2249.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ESRDHAF.
ProtClustDB	PRK05198.
Family and domain databases
HAMAP	MF_00056. KDO8P_synth. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006269. KDO8P_synthase. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01627.
PANTHER	PTHR21057:SF2. KDO8P_synthase. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01362. KDO8P_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1FAE6_ACIC5

Accession

Primary (citable) accession number: C1FAE6

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)