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C1FAE3 (C1FAE3_ACIC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP phosphoribosyltransferase HAMAP MF_00079
Short name=ATP-PRT HAMAP MF_00079
Short name=ATP-PRTase HAMAP MF_00079
EC=2.4.2.17 HAMAP MF_00079
Gene names
Name:hisG HAMAP MF_00079 EMBL ACO34256.1
Ordered Locus Names:ACP_2341
OrganismAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]
Taxonomic identifier240015 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length291 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity By similarity. HAMAP MF_00079

Catalytic activity

1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00079 SAAS SAAS013820

Cofactor

Magnesium By similarity. HAMAP MF_00079

Enzyme regulation

Feedback inhibited by histidine By similarity. HAMAP MF_00079

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9. HAMAP MF_00079 SAAS SAAS013820

Subcellular location

Cytoplasm By similarity HAMAP MF_00079.

Sequence similarities

Belongs to the ATP phosphoribosyltransferase family. Long subfamily. HAMAP MF_00079

Sequences

Sequence LengthMass (Da)Tools
C1FAE3 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 48E1886855339249

FASTA29132,232
        10         20         30         40         50         60 
MANKLRLGIP KGSLQDATIA LFERAGWHIY ANGRSYFPSI DDTEIECMLI RAQEMARYVN 

        70         80         90        100        110        120 
HGVLDAGLTG IDWVVESGLA VESVTSLVYA KQSRQKVRWV LAVPEDSKFE KAEDLGGKII 

       130        140        150        160        170        180 
ATELVEVTKR YFAERNVPVQ VEFSWGATEV KPPMLADAIV EVTETGSSLR ANRLRIIDTV 

       190        200        210        220        230        240 
MESETHLIAN RNAYNDAWKR EKLECLALML RGAIAAQGQV GLMLNVEKKN LQQILSVLPA 

       250        260        270        280        290 
LNSPTISELS NSEWVAVNTI LEESVVRDVV PRLKAANATG IVEYPLNKVV L

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001472 Genomic DNA. Translation: ACO34256.1.
RefSeqYP_002755385.1. NC_012483.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC1FAE3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7697851.
GenomeReviewsGene locus ACP_2341 in contig CP001472_GR.
KEGGaca:ACP_2341.
PATRIC20667939. VBIAciCap40988_2246.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAIMLHAPS.
ProtClustDBPRK00489.

Family and domain databases

HAMAPMF_00079. HisG_Long.
[Tree]
InterProIPR013820. ATP_PRibTrfase_cat.
IPR001348. ATP_PRibTrfase_HisG.
IPR020621. ATP_PRibTrfase_HisG_long.
IPR013115. HisG_C.
IPR011322. N-reg_PII-like_a/b.
IPR015867. N-reg_PII/ATP_PRibTrfase_C.
[Graphical view]
Gene3DG3DSA:3.30.70.120. PII_glnB. 1 hit.
KOK00765.
PANTHERPTHR21403. ATP_phspho_trans. 1 hit.
PfamPF01634. HisG. 1 hit.
PF08029. HisG_C. 1 hit.
[Graphical view]
SUPFAMSSF54913. N-reg_PII-like_a/b. 1 hit.
TIGRFAMsTIGR00070. HisG. 1 hit.
TIGR03455. HisG_C-term. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC1FAE3_ACIC5
AccessionPrimary (citable) accession number: C1FAE3
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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