C1F9P5 (C1F9P5_ACIC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Asparagine--tRNA ligase HAMAP-Rule MF_00534
EC=6.1.1.22 HAMAP-Rule MF_00534

Alternative name(s):
Asparaginyl-tRNA synthetase HAMAP-Rule MF_00534

Gene names

Name:	asnS HAMAP-Rule MF_00534 EMBL ACO34604.1
Ordered Locus Names:	ACP_2204

Organism

Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]

Taxonomic identifier

240015 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Fibrobacteres/Acidobacteria group › Acidobacteria › Acidobacteriia › Acidobacteriales › Acidobacteriaceae › Acidobacterium › Acidobacterium capsulatum

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn). HAMAP-Rule MF_00534 SAAS SAAS004522
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_00534
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00534.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00534 RuleBase RU003746

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP-Rule MF_00534 RuleBase RU003747 SAAS SAAS004522
Cellular component	Cytoplasm HAMAP-Rule MF_00534 SAAS SAAS004522
Ligand	ATP-binding HAMAP-Rule MF_00534 RuleBase RU003747 SAAS SAAS004522 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP-Rule MF_00534 RuleBase RU003747 SAAS SAAS004522 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	asparaginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP asparagine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1F9P5 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: E22603F0CA77B31E	FASTA	452	50,900
	10 20 30 40 50 60 MTEETNVTNT ATEAPLTTIA RIGEHEGKTI TLRGWLYNLR ESGKLLFPIF RDGSGTIQGI 70 80 90 100 110 120 VPKAAVAPEV FERIKGLTQE SSVIVTGKVR ADHRAPGGYE LDVENVEVVQ RVPEDTPFPI 130 140 150 160 170 180 SLKEHGTDFL MEHRHLWIRT PRQSAILRIR AEIIKAARDF LDDNGFILTD PPILTPAACE 190 200 210 220 230 240 GTSTLFPVEY FGDEAYLTQS GQLYIESTAL ALGKVYSFGP TFRAEKSKTR RHLTEFWMVE 250 260 270 280 290 300 PEWAYAGLDD LMGLAEQFIS FIVGRVLTRR AADLKVLGRD VAKLQSIQAP FPRLSYDEAA 310 320 330 340 350 360 QMLNDAHAKG LLEHPFEYGN DFGSPDETYI SSQFDRPVMV HRYPAAVKAF YMEPDPENSK 370 380 390 400 410 420 YALCVDVLAP EGYGEIIGGS QRISSYELLK QRIEDHQLPL EAFQWYLDLR RYGSVPHSGF 430 440 450 GMGIERAVAW ICGLEHVRET IPFARTLNRI YP

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51196 / DSM 11244 / JCM 7670.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001472 Genomic DNA. Translation: ACO34604.1.
RefSeq	YP_002755255.1. NC_012483.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	240015.ACP_2204.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACO34604; ACO34604; ACP_2204.
GeneID	7700173.
KEGG	aca:ACP_2204.
PATRIC	20667663. VBIAciCap40988_2110.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0017.
HOGENOM	HOG000226034.
KO	K01893.
OMA	HEQGFYW.
ProtClustDB	PRK03932.
Enzyme and pathway databases
BioCyc	ACAP240015:GI5H-3361-MONOMER.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
HAMAP	MF_00534. Asn_tRNA_synth.
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II. IPR004522. Asn-tRNA-ligase_IIb. IPR002312. Asp/Asn-tRNA-synth_IIb. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. [Graphical view]
PANTHER	PTHR22594. PTHR22594. 1 hit. PTHR22594:SF6. PTHR22594:SF6. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00457. asnS. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1F9P5_ACIC5

Accession

Primary (citable) accession number: C1F9P5

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)