C1F8V3 (C1F8V3_ACIC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartate carbamoyltransferase HAMAP MF_00001
EC=2.1.3.2 HAMAP MF_00001

Alternative name(s):
Aspartate transcarbamylase HAMAP MF_00001

Gene names

Name:	pyrB HAMAP MF_00001 EMBL ACO34543.1
Ordered Locus Names:	ACP_2012

Organism

Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]

Taxonomic identifier

240015 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP MF_00001
Sequence similarities	Belongs to the ATCase/OTCase family. HAMAP MF_00001 RuleBase RU003634

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis HAMAP MF_00001
Molecular function	Transferase HAMAP MF_00001 RuleBase RU003634 EMBL ACO34543.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	amino acid binding Inferred from electronic annotation. Source: InterPro aspartate carbamoyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1F8V3 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 0A8D044248D650B6	FASTA	342	36,768
	10 20 30 40 50 60 MAPRKASTAA RARTAKSKAA PTLSLHPGAL VSVRDLTPER ARAILQLADK LETQDVFERA 70 80 90 100 110 120 KRLRKRRVAL LFYESSTRTR TSFELAAKSL GADTTLVSAL SSSIEKGESL KDTGITLKAL 130 140 150 160 170 180 GAECIILRSP YSGAPYLLAK STGLPVLNAG DGMHEHPSQA LLDLRTMLRF LGIKAAKLSP 190 200 210 220 230 240 TALKGVTVTI CGDILHSRVA RSNALLLPRL GAQVTFCGPT PLLPDLAADI GPGVSVERDF 250 260 270 280 290 300 EAALRRSQIV MMLRIQAERL AGLKIDLDDY KQHYQANSER VAACAPKALI MHPGPIIRGL 310 320 330 340 EITSEVADGP QSAIAEQVHH GLAIRMALLA QALDKSKQRT RA

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001472 Genomic DNA. Translation: ACO34543.1.
RefSeq	YP_002755071.1. NC_012483.1.
3D structure databases
ProteinModelPortal	C1F8V3.
ModBase	Search...
Protein-protein interaction databases
STRING	C1F8V3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7699530.
GenomeReviews	Gene locus ACP_2012 in contig CP001472_GR.
KEGG	aca:ACP_2012.
PATRIC	20667301. VBIAciCap40988_1934.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LQRERMS.
Family and domain databases
HAMAP	MF_00001. Asp_carb_tr. [Tree]
InterPro	IPR006132. Asp/Orn_carbamoyltranf_P-bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn-bd. IPR002082. Asp_carbamoyltransf_euk. [Graphical view]
KO	K00609.
Pfam	PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view]
PRINTS	PR00100. AOTCASE. PR00101. ATCASE.
SUPFAM	SSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMs	TIGR00670. Asp_carb_tr. 1 hit.
PROSITE	PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1F8V3_ACIC5

Accession

Primary (citable) accession number: C1F8V3

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)