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C1F8G5

- C1F8G5_ACIC5

UniProt

C1F8G5 - C1F8G5_ACIC5

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd1

Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciACAP240015:GKF4-89-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icd1Imported
    Ordered Locus Names:ACP_0089Imported
    OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)Imported
    Taxonomic identifieri240015 [NCBI]
    Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
    ProteomesiUP000002207: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi240015.ACP_0089.

    Structurei

    3D structure databases

    ProteinModelPortaliC1F8G5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0538.
    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 2 hits.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C1F8G5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQASYNGVSL PEGGQPITYS GGKYTVPDHP IIPFIEGDGT GRDIWRASQR    50
    VFDAAVHKAY GGQRSVKWFE IFAGEKAFRE FKTWLPDDSV KAATDLRVSI 100
    KGPLTTPVGG GIRSLNVALR QIMDLYACVR PVKYYAGVPS PVKHPEKLDV 150
    VIFRENTEDV YAGIEFKQGT PEAKKLIDFL NDEMLKGGKK KVRSDSGVGI 200
    KPISITGTKR LVRYAIQYAI ENGRRSVTLV HKGNIQKFTE GAFREWGYEV 250
    AVEEFREHVV TERESWILGN AEANPGLTVE QNAAMIEPGL EFGSEDFRKD 300
    LYAEIKGVLD SIGQSHGAGK WKQKILINDR IADSIFQQVI IRPDEYDILA 350
    CPNLNGDYIS DACAAQVGGL GIAPGANIGD GYAVFEATHG TAPKYADKDV 400
    INPGSVMLSG VMMFEFLGWK EAARLIESAM EKTIQQKHVT YDFERQMPGA 450
    TKVKTSEFAT KMIENM 466
    Length:466
    Mass (Da):51,501
    Last modified:May 26, 2009 - v1
    Checksum:i4E35E746973523BB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001472 Genomic DNA. Translation: ACO34056.1.
    RefSeqiWP_012680497.1. NC_012483.1.
    YP_002753239.1. NC_012483.1.

    Genome annotation databases

    EnsemblBacteriaiACO34056; ACO34056; ACP_0089.
    GeneIDi7697831.
    KEGGiaca:ACP_0089.
    PATRICi20663579. VBIAciCap40988_0090.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001472 Genomic DNA. Translation: ACO34056.1 .
    RefSeqi WP_012680497.1. NC_012483.1.
    YP_002753239.1. NC_012483.1.

    3D structure databases

    ProteinModelPortali C1F8G5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 240015.ACP_0089.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO34056 ; ACO34056 ; ACP_0089 .
    GeneIDi 7697831.
    KEGGi aca:ACP_0089.
    PATRICi 20663579. VBIAciCap40988_0090.

    Phylogenomic databases

    eggNOGi COG0538.
    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Enzyme and pathway databases

    BioCyci ACAP240015:GKF4-89-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 2 hits.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51196 / DSM 11244 / JCM 7670Imported.

    Entry informationi

    Entry nameiC1F8G5_ACIC5
    AccessioniPrimary (citable) accession number: C1F8G5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 26, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3