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C1F8G5

- C1F8G5_ACIC5

UniProt

C1F8G5 - C1F8G5_ACIC5

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Protein
Isocitrate dehydrogenase [NADP]
Gene
icd1, ACP_0089
Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  3. magnesium ion binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciACAP240015:GKF4-89-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icd1Imported
Ordered Locus Names:ACP_0089Imported
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)Imported
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
ProteomesiUP000002207: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi240015.ACP_0089.

Structurei

3D structure databases

ProteinModelPortaliC1F8G5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0538.
HOGENOMiHOG000021113.
KOiK00031.
OMAiCLRPIRY.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 2 hits.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1F8G5-1 [UniParc]FASTAAdd to Basket

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MQASYNGVSL PEGGQPITYS GGKYTVPDHP IIPFIEGDGT GRDIWRASQR    50
VFDAAVHKAY GGQRSVKWFE IFAGEKAFRE FKTWLPDDSV KAATDLRVSI 100
KGPLTTPVGG GIRSLNVALR QIMDLYACVR PVKYYAGVPS PVKHPEKLDV 150
VIFRENTEDV YAGIEFKQGT PEAKKLIDFL NDEMLKGGKK KVRSDSGVGI 200
KPISITGTKR LVRYAIQYAI ENGRRSVTLV HKGNIQKFTE GAFREWGYEV 250
AVEEFREHVV TERESWILGN AEANPGLTVE QNAAMIEPGL EFGSEDFRKD 300
LYAEIKGVLD SIGQSHGAGK WKQKILINDR IADSIFQQVI IRPDEYDILA 350
CPNLNGDYIS DACAAQVGGL GIAPGANIGD GYAVFEATHG TAPKYADKDV 400
INPGSVMLSG VMMFEFLGWK EAARLIESAM EKTIQQKHVT YDFERQMPGA 450
TKVKTSEFAT KMIENM 466
Length:466
Mass (Da):51,501
Last modified:May 26, 2009 - v1
Checksum:i4E35E746973523BB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001472 Genomic DNA. Translation: ACO34056.1.
RefSeqiWP_012680497.1. NC_012483.1.
YP_002753239.1. NC_012483.1.

Genome annotation databases

EnsemblBacteriaiACO34056; ACO34056; ACP_0089.
GeneIDi7697831.
KEGGiaca:ACP_0089.
PATRICi20663579. VBIAciCap40988_0090.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001472 Genomic DNA. Translation: ACO34056.1 .
RefSeqi WP_012680497.1. NC_012483.1.
YP_002753239.1. NC_012483.1.

3D structure databases

ProteinModelPortali C1F8G5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 240015.ACP_0089.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO34056 ; ACO34056 ; ACP_0089 .
GeneIDi 7697831.
KEGGi aca:ACP_0089.
PATRICi 20663579. VBIAciCap40988_0090.

Phylogenomic databases

eggNOGi COG0538.
HOGENOMi HOG000021113.
KOi K00031.
OMAi CLRPIRY.
OrthoDBi EOG6SNDTP.

Enzyme and pathway databases

BioCyci ACAP240015:GKF4-89-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 2 hits.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51196 / DSM 11244 / JCM 7670.

Entry informationi

Entry nameiC1F8G5_ACIC5
AccessioniPrimary (citable) accession number: C1F8G5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: September 3, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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