C1F714 (C1F714_ACIC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III, alpha subunit EMBL ACO32268.1
EC=2.7.7.7 EMBL ACO32268.1

Gene names

Name:	dnaE3 EMBL ACO32268.1
Ordered Locus Names:	ACP_3484

Organism

Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]

Taxonomic identifier

240015 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length	1173 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1F714 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 69605A9ACA134EEE	FASTA	1,173	131,137
	10 20 30 40 50 60 MAEFTHLHLH TDYSLLDGAC DVEKLVGHVA SIGQTSVAIT DHGNIYGAVH FFEAAKKKGI 70 80 90 100 110 120 KPILGCELYI CQKEDHRADP QGDDYNHLLV LAESEEGYRN LVRITSEASL HGFYRKPRIS 130 140 150 160 170 180 KKYLAEHAAG LIGFSGCLAG EFCQNLMADN YQAARATAAQ YQDIFGRGNF FLEIQDQGLE 190 200 210 220 230 240 LEKKIHADMF RLEKDLDIPL VATNDSHYLC EDDHHAHDVL LCVQTAGSIH DPKRFKFDSD 250 260 270 280 290 300 QFYVKSAAEM ERLFPHAPEV VSRTMQFAER CNLKLNKVDN PFPEFAVPPG HTIDSYFEHV 310 320 330 340 350 360 CREGFKKRLD TAIRHLQDRG ILRSPISDYE ARLEREIGII KQMKFSGYFL IVWDFIRYAK 370 380 390 400 410 420 DHDIPVGPGR GSAAGSLVGY VMEITDIDPL QNVLLFERFL NPERVSMPDI DIDFCMNRRG 430 440 450 460 470 480 EVIEYVTRKY GREQVAQIIT FNTMAAKAAI KDVGRALDMP YGDVDRIAKM IPATIGVTID 490 500 510 520 530 540 QALTDSPQLQ EAYEGNTQIR ELIDTAKRLE GLVRGAGVHA AGVVIAPRPL TDLVPLSRSK 550 560 570 580 590 600 NDEIVTAYDM KAVEKMGLLK MDFLGLTTLT VIDDCLKMIR KNRGETVDMA KVPLDDQETY 610 620 630 640 650 660 ERVFHRALTS GVFQFESGGM RDVLRRYKPT CVEDLTALNA LYRPGPIQGG MIDDFIERKW 670 680 690 700 710 720 GRRKVEYELP PLETILKETL GVIVYQEQVM QIANVLAGYS LGEADLLRRA MGKKNPEEMA 730 740 750 760 770 780 KQRDRFVSGA LEREFPKDKI VKIFDLMEQF AGYGFNKSHS AAYALLAYHT AWLKTHYPVE 790 800 810 820 830 840 FMAALLTSEI SKPENVVKYI QECREIEIPV EPPDVLFSDA DFTPHGKSIR FGLTAIKNVG 850 860 870 880 890 900 RNAIDSILDA RGKLAAEGKS FQNFWEFCEK VDLRLMNKRV IESLIKAGAL DSFGRRAQLM 910 920 930 940 950 960 ASVDKAIERA QKAQRDEAAG QSGLFGLFDA DAPASASPAD DLPNVPDWEE ALRLQSEKEV 970 980 990 1000 1010 1020 LGFFVSGHPL DRYAEKLRNL PGIIDTATAL EMKPAPPTGR RGQSNENEIA IAGMIVGLKV 1030 1040 1050 1060 1070 1080 AKSKRSGDLY AQASLEDATG KIDLICFPRD YERLADSLKM EAPVVVRGAL RAEEEAAPKL 1090 1100 1110 1120 1130 1140 AISSIQALDD VKVKLPSNVR IRVQLDRISE STLEELHQLI SAVPGPGKMM LNLEKKGEYC 1150 1160 1170 VVMEPEGFTV AADRAFIDQA ELLLGRGSVQ ALD

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001472 Genomic DNA. Translation: ACO32268.1.
RefSeq	YP_002756478.1. NC_012483.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C1F714.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7700708.
GenomeReviews	Gene locus ACP_3484 in contig CP001472_GR.
KEGG	aca:ACP_3484.
PATRIC	20670169. VBIAciCap40988_3340.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	RVLQMPY.
ProtClustDB	CLSK774840.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1F714_ACIC5

Accession

Primary (citable) accession number: C1F714

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)