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C1F6Z8 (C1F6Z8_ACIC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroxy-acid dehydratase HAMAP MF_00012
Short name=DAD HAMAP MF_00012
EC=4.2.1.9 HAMAP MF_00012
Gene names
Name:ilvD HAMAP MF_00012 EMBL ACO32516.1
Ordered Locus Names:ACP_3467
OrganismAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]
Taxonomic identifier240015 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length562 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O. HAMAP MF_00012

Cofactor

Binds 1 4Fe-4S cluster By similarity. HAMAP MF_00012

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4. HAMAP MF_00012

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4. HAMAP MF_00012

Sequence similarities

Belongs to the IlvD/Edd family. HAMAP MF_00012

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1291Iron-sulfur (4Fe-4S) By similarity HAMAP MF_00012
Metal binding2011Iron-sulfur (4Fe-4S) By similarity HAMAP MF_00012

Sequences

Sequence LengthMass (Da)Tools
C1F6Z8 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 9F8D2F77C8F88DEA

FASTA56258,966
        10         20         30         40         50         60 
MSSEQNGSAK KNSVALTEGP NRAPARAMLR AIGFTRDDLR KPIIGIANTW TEIGPCNFHL 

        70         80         90        100        110        120 
RQIAEAVKQG IREAGGTPME FNTVTISDGI TMGTEGMKAS LVSREVIADS IELVTRGNLF 

       130        140        150        160        170        180 
DGLVCIAGCD KNLPGTVMAL ARLDVPGLML YGGSIAPGHL NGKDLTVQDV FEAVGSHAAG 

       190        200        210        220        230        240 
KLDDAGLEAV EANACPGAGA CGGQFTANTM AMACEFMGIS PMSISGVPAF LPEKLASAKE 

       250        260        270        280        290        300 
AGKLVLELAK RDLRPSQLIT KESLENAIAS VAASGGSTNA VLHFLAIAHE RGIALSIDDF 

       310        320        330        340        350        360 
DRISEKTPLL CDMKPGGKYV AADYQKAGGS RLLAKRLIEG GYIHSDCLNA SGRTLAEEAA 

       370        380        390        400        410        420 
LAVEEPGQKV IFPATNALKP TGGLVILKGN LAPEGCVIKV AGHSRLTHRG PARVFDREQD 

       430        440        450        460        470        480 
AFAAVENGSI QPDDVMVIRY EGPKGGPGMR EMLGVTAAIA GIPALSETVA LLTDGRFSGA 

       490        500        510        520        530        540 
TRGLMAGHVS PEAAVRGPIA AVRNGDMIHF DIPNRRLDVE LTDAQIEERL KDWKEPAPHF 

       550        560 
SRGVFKKYVD TVSSAARGAV TN

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001472 Genomic DNA. Translation: ACO32516.1.
RefSeqYP_002756462.1. NC_012483.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC1F6Z8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7698120.
GenomeReviewsGene locus ACP_3467 in contig CP001472_GR.
KEGGaca:ACP_3467.
PATRIC20670133. VBIAciCap40988_3322.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMANMPGAMI.
ProtClustDBPRK00911.

Family and domain databases

HAMAPMF_00012. IlvD.
[Tree]
InterProIPR015928. Aconitase/3IPM_dehydase_swvl.
IPR004404. DihydroxyA_deHydtase.
IPR000581. DiOHA_6PGluconate_deHydtase.
IPR020558. DiOHA_6PGluconate_deHydtase_CS.
[Graphical view]
KOK01687.
PANTHERPTHR21000. ILVD_EDD_family. 1 hit.
PfamPF00920. ILVD_EDD. 1 hit.
[Graphical view]
SUPFAMSSF52016. Aconitase/3IPM_dehydase_swvl. 1 hit.
TIGRFAMsTIGR00110. IlvD. 1 hit.
PROSITEPS00886. ILVD_EDD_1. 1 hit.
PS00887. ILVD_EDD_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1F6Z8_ACIC5
AccessionPrimary (citable) accession number: C1F6Z8
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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