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Protein

ATP-dependent Clp protease ATP-binding subunit ClpX

Gene

clpX

Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi123 – 130ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation, Hydrolase, ProteaseImported
LigandATP-bindingUniRule annotationSAAS annotationImported, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent Clp protease ATP-binding subunit ClpXUniRule annotationSAAS annotation
Gene namesi
Name:clpXUniRule annotationImported
Ordered Locus Names:ACP_3432Imported
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)Imported
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
Proteomesi
  • UP000002207 Componenti: Chromosome

Interactioni

Subunit structurei

Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.UniRule annotationSAAS annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi240015.ACP_3432.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 53zf-C4_ClpXInterPro annotationAdd BLAST44
Domaini114 – 267AAAInterPro annotationAdd BLAST154
Domaini326 – 419ClpB_D2-smallInterPro annotationAdd BLAST94

Sequence similaritiesi

Belongs to the ClpX chaperone family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CHN. Bacteria.
COG1219. LUCA.
HOGENOMiHOG000010093.
KOiK03544.
OMAiDIMYDLP.
OrthoDBiPOG091H01U4.

Family and domain databases

HAMAPiMF_00175. ClpX. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004487. Clp_protease_ATP-bd_su_ClpX.
IPR027417. P-loop_NTPase.
IPR010603. Znf_CppX_C4.
PANTHERiPTHR11262. PTHR11262. 1 hit.
PfamiView protein in Pfam
PF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF06689. zf-C4_ClpX. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM01086. ClpB_D2-small. 1 hit.
SM00994. zf-C4_ClpX. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00382. clpX. 1 hit.

Sequencei

Sequence statusi: Complete.

C1F6W3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTRTGSDDS LRCSFCHKSQ DAVAKLISSP SDYPRAYICD ECVAVCNSIL
60 70 80 90 100
EDDRAEAPAG AAPTQLPKPL EVKAFLDEYV IGQEQTKKKL AVAVYNHYKR
110 120 130 140 150
IQMNRTRGND VELAKSNILL VGPTGSGKTL LAHTLAKMLD VPFAIVDATT
160 170 180 190 200
LTEAGYVGED VENIILKLLQ AADGDVARAQ TGIIYIDEID KIGRKDENPS
210 220 230 240 250
ITRDVSGEGV QQALLKILEG TVANVPPQGG RKHPHQEFTP VDTTNILFIC
260 270 280 290 300
GGAFVGLERV VGRRVGKKAL GFKAIAEKDQ QENGQTTRTQ RDTELLRMAE
310 320 330 340 350
PQDLIRYGLI PEFVGRLPVI GILDELDEAA LVEILTKPRN AILKQYQKLF
360 370 380 390 400
EFEGVNLVFS EEAAHAIALE ALDRKVGARG LRMILEELML DLMYHLPSNK
410 420
RVSDLVIDAE MVKKRDLSLS LLDKAG
Length:426
Mass (Da):46,843
Last modified:May 26, 2009 - v1
Checksum:i7673666AE03C4B9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA. Translation: ACO31650.1.
RefSeqiWP_015898461.1. NC_012483.1.

Genome annotation databases

EnsemblBacteriaiACO31650; ACO31650; ACP_3432.
KEGGiaca:ACP_3432.

Similar proteinsi

Entry informationi

Entry nameiC1F6W3_ACIC5
AccessioniPrimary (citable) accession number: C1F6W3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: June 7, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported