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C1F698 (C1F698_ACIC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH HAMAP MF_00191 EMBL ACO32491.1
Ordered Locus Names:ACP_3328
OrganismAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]
Taxonomic identifier240015 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length338 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191 SAAS SAAS003451

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191 SAAS SAAS003451

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191 SAAS SAAS003451

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191 SAAS SAAS003451

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
C1F698 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 6DFAEDF7879D6F70

FASTA33836,421
        10         20         30         40         50         60 
MTTITDQPTP AHVSAPDGER KVLLLKPRGF CAGVVRAVDI VRIALETFGA PIYVRKEIVH 

        70         80         90        100        110        120 
NRFVVNELAE KGAIFVEDID QVPEGSRVIY SAHGVSPAVR QQSKDRNLRV IDATCPLVTK 

       130        140        150        160        170        180 
VHVEAVKFAR QGYSLVLIGH RDHEEIEGTL GEAPDVTTVV SSAAEVAALE VPDPNRVAYL 

       190        200        210        220        230        240 
TQTTLSLDEA RDMIEALKKK FPNIVGPHSQ DICYATENRQ VAVKNVAHQA DLVLVVGSNN 

       250        260        270        280        290        300 
SSNSNRLVEV SRNLGTKGYL IDNSKAIRPE WLEGVATVAV TAGASAPEVL VEDVVKYLGS 

       310        320        330 
KGFGSVEEVE VMPENVRFGL PPEIVQAIQA APSSPVSA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001472 Genomic DNA. Translation: ACO32491.1.
RefSeqYP_002756327.1. NC_012483.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC1F698.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7697785.
GenomeReviewsGene locus ACP_3328 in contig CP001472_GR.
KEGGaca:ACP_3328.
PATRIC20669855. VBIAciCap40988_3185.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAAMAPECD.
ProtClustDBCLSK774625.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC1F698_ACIC5
AccessionPrimary (citable) accession number: C1F698
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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