C1F681 (C1F681_ACIC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4-hydroxyphenylpyruvate dioxygenase EMBL ACO32550.1
EC=1.13.11.27 EMBL ACO32550.1

Gene names

Name:	hppD EMBL ACO32550.1
Ordered Locus Names:	ACP_3311

Organism

Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]

Taxonomic identifier

240015 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length	374 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 iron ion per subunit By similarity. PIRSR PIRSR009283-1
Sequence similarities	Belongs to the 4HPPD family. PIRSR PIRSR009283-1

Ontologies

Keywords
Ligand	Iron PIRSR PIRSR009283-1 Metal-binding PIRSR PIRSR009283-1 Pyruvate EMBL ACO32550.1
Molecular function	Dioxygenase EMBL ACO32550.1 Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-hydroxyphenylpyruvate dioxygenase activity Inferred from electronic annotation. Source: EC lactoylglutathione lyase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	180	1	Iron By similarity PIRSR PIRSR009283-1
	Metal binding	263	1	Iron By similarity PIRSR PIRSR009283-1
	Metal binding	342	1	Iron By similarity PIRSR PIRSR009283-1

Sequences

	Sequence		Length	Mass (Da)
	C1F681 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 0B477D43DBC32D07	FASTA	374	42,464
	10 20 30 40 50 60 MSTLVHPEVA TQKDFLPLNG TDHVEFYVGN AKQAAYFYRV AFGFQLVAYA GPETGVRDRA 70 80 90 100 110 120 SYVLQQNKIR FVLTTPLRPD GEIAAHIHLH GDGIRDVALW VDDARQAWKE TTKRGARSVR 130 140 150 160 170 180 EPFELKDEHG TVKMASIAAY GDTVHTFVER GSYHGVFLPG YRAEAEDTIA RPTGLLHVDH 190 200 210 220 230 240 MVGNVGWNEM NRWVDFYADI MGFSLYQHFD DKDISTEYSA LMSKVMANGN GRVKFPINEP 250 260 270 280 290 300 AEGRRKSQIE EYLEFYHGPG VQHVAMATHD ILETVSKLQA QGVAFLKVPH SYYTELEGRV 310 320 330 340 350 360 GKIDEPIEEL EKLGILVDRD DEGYMLQIFT KPVEDRPTLF YEIIQRKGSR SFGKGNFKAL 370 FEAIEREQEL RGNL

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001472 Genomic DNA. Translation: ACO32550.1.
RefSeq	YP_002756310.1. NC_012483.1.
3D structure databases
ProteinModelPortal	C1F681.
ModBase	Search...
Protein-protein interaction databases
STRING	C1F681.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7697836.
GenomeReviews	Gene locus ACP_3311 in contig CP001472_GR.
KEGG	aca:ACP_3311.
PATRIC	20669819. VBIAciCap40988_3167.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	HCVGNVE.
ProtClustDB	CLSK902447.
Family and domain databases
InterPro	IPR005956. 4OHPhenylPyrv_dOase. IPR004360. Glyas_Fos-R_dOase. IPR018146. Glyoxalase_1_CS. [Graphical view]
KO	K00457.
PANTHER	PTHR11959. HPP_dOase. 1 hit.
Pfam	PF00903. Glyoxalase. 2 hits. [Graphical view]
PIRSF	PIRSF009283. HPP_dOase. 1 hit.
TIGRFAMs	TIGR01263. 4HPPD. 1 hit.
PROSITE	PS00934. GLYOXALASE_I_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1F681_ACIC5

Accession

Primary (citable) accession number: C1F681

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)