C1F654 (C1F654_ACIC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aspartate-semialdehyde dehydrogenase EMBL ACO33694.1
EC=1.2.1.11 EMBL ACO33694.1

Gene names

Name:	asd EMBL ACO33694.1
Ordered Locus Names:	ACP_1463

Organism

Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]

Taxonomic identifier

240015 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Fibrobacteres/Acidobacteria group › Acidobacteria › Acidobacteriia › Acidobacteriales › Acidobacteriaceae › Acidobacterium › Acidobacterium capsulatum

Protein attributes

Sequence length	353 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family. RuleBase RU004041

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ACO33694.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	aspartate metabolic process Inferred from electronic annotation. Source: InterPro isoleucine biosynthetic process Inferred from electronic annotation. Source: InterPro lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro methionine biosynthetic process Inferred from electronic annotation. Source: InterPro threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro NADP binding Inferred from electronic annotation. Source: InterPro aspartate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	147	1	Acyl-thioester intermediate By similarity PIRSR PIRSR000148-1
	Active site	240	1	Proton acceptor By similarity PIRSR PIRSR000148-1

Sequences

	Sequence		Length	Mass (Da)
	C1F654 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 1804F18B4C720718	FASTA	353	38,210
	10 20 30 40 50 60 MRQKIGILGA TGMVGQRFIQ LLEHHPWFEV AWLAASDRSS GKRYGDAVRW KLDTPIPERI 70 80 90 100 110 120 AAMEISPAQP EGAPQVIFAA LDADIAREME PKFAAAGCAV ISNSSAFRMQ ADVPLVIPEV 130 140 150 160 170 180 NADHLALLEQ QEWRKQSGGY IVTNPNCSAI GLVLALKPLE ERFGIESIFV STMQAVSGAG 190 200 210 220 230 240 YPGVASLDIM GNVVPFIKNE EEKLQEETLR LLGKLQSNLV HPLDAKITAH CNRVAVEDGH 250 260 270 280 290 300 TESVSVKLKR KATREDLLAA WQEFAPLAGR DLPTAPAQPV ETIEAVDRPQ PRLDRMRGAG 310 320 330 340 350 MAATVGRVRP CSLLDWKFTV LSHNTIRGAA GAALLNAELL VSLGKLNPSA VPA

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51196 / DSM 11244 / JCM 7670.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001472 Genomic DNA. Translation: ACO33694.1.
RefSeq	YP_002754549.1. NC_012483.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	240015.ACP_1463.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACO33694; ACO33694; ACP_1463.
GeneID	7699313.
KEGG	aca:ACP_1463.
PATRIC	20666239. VBIAciCap40988_1409.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0136.
HOGENOM	HOG000013358.
KO	K00133.
OMA	VIDGHTE.
ProtClustDB	PRK08664.
Enzyme and pathway databases
BioCyc	ACAP240015:GI5H-2439-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR005676. Asp_semi-ald_DH_pep-lack. IPR012080. Asp_semialdehyde_DH. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view]
Pfam	PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view]
PIRSF	PIRSF000148. ASA_dh. 1 hit.
SMART	SM00859. Semialdhyde_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR00978. asd_EA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1F654_ACIC5

Accession

Primary (citable) accession number: C1F654

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)