C1F4W4 (C1F4W4_ACIC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903

Gene names

Name:	proC EMBL ACO32750.1
Ordered Locus Names:	ACP_1238

Organism

Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]

Taxonomic identifier

240015 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length	280 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903
Pathway	Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903
Sequence similarities	Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Proline biosynthesis RuleBase RU003903
Ligand	NADP RuleBase RU003903
Molecular function	Oxidoreductase RuleBase RU003903 EMBL ACO32750.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro pyrroline-5-carboxylate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1F4W4 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: E1D8CCC67708843B	FASTA	280	28,933
	10 20 30 40 50 60 MTIPTSSSIS VAQARVAVLG AGKMGGILLQ AFLKQNILRP DQIVATVAHE DRALALSAQW 70 80 90 100 110 120 GVEVTTDNLA AAKQANVILL GVKPFQIAGL MEEIRPALDG TKLLVSFAAS VKTAAIEEAA 130 140 150 160 170 180 GMALPVIRTM PNTPSMLGAG ISALCSGKNV LPEHLQLASA LFEAVGRTVV VDEKHMDAVT 190 200 210 220 230 240 GLSASGPAYI YIILEALAEA GVKVGLPRDI ATLLAAQTTL GAAKMVLDTG YHPALLKDAV 250 260 270 280 TTPAGCTIDG ILELEEGGLR VTLIKAVMRA TQRARELAAG

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001472 Genomic DNA. Translation: ACO32750.1.
RefSeq	YP_002754333.1. NC_012483.1.
3D structure databases
ProteinModelPortal	C1F4W4.
ModBase	Search...
Protein-protein interaction databases
STRING	C1F4W4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7701156.
GenomeReviews	Gene locus ACP_1238 in contig CP001472_GR.
KEGG	aca:ACP_1238.
PATRIC	20665803. VBIAciCap40988_1193.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FDAFTGM.
ProtClustDB	CLSK2314885.
Family and domain databases
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR016040. NAD(P)-bd_dom. IPR004455. NADP_OxRdtase_F420. IPR000304. Pyrroline-COOH_reductase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00286.
PANTHER	PTHR11645. P5CR. 1 hit.
Pfam	PF03807. F420_oxidored. 1 hit. [Graphical view]
PIRSF	PIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR00112. ProC. 1 hit.
PROSITE	PS00521. P5CR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1F4W4_ACIC5

Accession

Primary (citable) accession number: C1F4W4

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)