Skip Header

Contribute Send feedback
Read comments (?) or add your own

C1F4C8 (C1F4C8_ACIC5) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Dihydroorotate dehydrogenase HAMAP MF_00224
Short name=DHOD HAMAP MF_00224
Short name=DHODase HAMAP MF_00224
Short name=DHOdehase HAMAP MF_00224
EC=1.3.-.- HAMAP MF_00224
Gene names
Name:pyrD HAMAP MF_00224 EMBL ACO33627.1
Ordered Locus Names:ACP_2970
OrganismAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]
Taxonomic identifier240015 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate By similarity. HAMAP MF_00224

Catalytic activity

(S)-dihydroorotate + acceptor = orotate + reduced acceptor. HAMAP MF_00224

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_00224 SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway. HAMAP MF_00224

Subcellular location

Cytoplasm By similarity HAMAP MF_00224.

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. HAMAP MF_00224

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1291Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
C1F4C8 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: E05A6668F1B5EAB5

FASTA30532,281
        10         20         30         40         50         60 
MDMRVTVAGI EFANPVIAAS GTFAYGIEFE DIVSLDRIGG FVTKGISREP MAGNAAPRLI 

        70         80         90        100        110        120 
ETSAGMINAI GLQNIGVEAF LRDKLPPLAR YKCAVIVNVF GYQVEDYVAV IRKLNEAEGI 

       130        140        150        160        170        180 
AAYEINASCP NTKHGGMAFG ADHGALAELV AHCRHYSRRP VIVKLSPNVT SIAAMARCAE 

       190        200        210        220        230        240 
SSGADAISLV NTFVSLAIDV ETRQPRIRNI TGGLSGPAIK PIAVRMVWEA AQAVKIPVIG 

       250        260        270        280        290        300 
MGGIATAEDA VEFLLAGATA VQVGTASYAD PRAIENISHS LAHWCARRHI ARVSELTGAM 


ELPTK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001472 Genomic DNA. Translation: ACO33627.1.
RefSeqYP_002755980.1. NC_012483.1.

3D structure databases

ProteinModelPortalC1F4C8.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1F4C8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7698529.
GenomeReviewsGene locus ACP_2970 in contig CP001472_GR.
KEGGaca:ACP_2970.
PATRIC20669173. VBIAciCap40988_2845.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVALRMVW.
ProtClustDBCLSK774280.

Family and domain databases

HAMAPMF_00224. DHO_dh_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR005720. Dihydroorotate_DH.
IPR024920. Dihydroorotate_DH_1.
IPR012135. Dihydroorotate_DH_1_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01037. PyrD_sub1_fam. 1 hit.
PROSITEPS00912. DHODEHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1F4C8_ACIC5
AccessionPrimary (citable) accession number: C1F4C8
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info