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C1F461

- MRAY_ACIC5

UniProt

C1F461 - MRAY_ACIC5

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Protein
Phospho-N-acetylmuramoyl-pentapeptide-transferase
Gene
mraY, ACP_1089
Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity.UniRule annotation

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity Source: UniProtKB-EC
  2. phospho-N-acetylmuramoyl-pentapeptide-transferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
  4. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciACAP240015:GKF4-1067-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC:2.7.8.13)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferase
Gene namesi
Name:mraY
Ordered Locus Names:ACP_1089
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
ProteomesiUP000002207: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei27 – 4721Helical; Reviewed prediction
Add
BLAST
Transmembranei71 – 9121Helical; Reviewed prediction
Add
BLAST
Transmembranei94 – 11421Helical; Reviewed prediction
Add
BLAST
Transmembranei139 – 15921Helical; Reviewed prediction
Add
BLAST
Transmembranei182 – 20221Helical; Reviewed prediction
Add
BLAST
Transmembranei216 – 23621Helical; Reviewed prediction
Add
BLAST
Transmembranei252 – 27221Helical; Reviewed prediction
Add
BLAST
Transmembranei280 – 30021Helical; Reviewed prediction
Add
BLAST
Transmembranei305 – 32521Helical; Reviewed prediction
Add
BLAST
Transmembranei354 – 37421Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation
PRO_1000117153Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi240015.ACP_1089.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0472.
HOGENOMiHOG000275122.
KOiK01000.
OMAiQIHYVSG.
OrthoDBiEOG69GZPZ.

Family and domain databases

HAMAPiMF_00038. MraY.
InterProiIPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view]
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiPF00953. Glycos_transf_4. 1 hit.
PF10555. MraY_sig1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00445. mraY. 1 hit.
PROSITEiPS01348. MRAY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1F461-1 [UniParc]FASTAAdd to Basket

« Hide

MLYWLLYQKL FPYFRPFRIF RYLTFRTAFA SLTALLIALL IGPYVIEKLR    50
EFQIGQYIRE EGPQAHQKKA GTPTMGGVLI CIAILLPTLL WSDLSDPFVW 100
IVMLSTLAFG AIGFADDYIK VVHRRNLGLT ARAKMTYQIL ASAAIGVALV 150
VLQGQGSYST DLMVPFAKSL RPRFSIPALL HVPHLAYFAF IPFVIFVIIV 200
IVGSSNAVNL TDGLDGLAIG CTIIAAGALT VLTYVSGHAV FADYLELQRM 250
PMVGEVTIFC GAMVGASIGF LWYNAHPAQI FMGDVGSLAL GGAIATVAVV 300
IKQELLLPFI GGIFVLEALS VILQVGSYKL RKKRIFKMAP LHHHFELIGW 350
SESKVIVRFW IAALVFALFA LTTLKLR 377
Length:377
Mass (Da):41,561
Last modified:May 26, 2009 - v1
Checksum:i093E49E93231F4A7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001472 Genomic DNA. Translation: ACO32749.1.
RefSeqiWP_015896247.1. NC_012483.1.
YP_002754194.1. NC_012483.1.

Genome annotation databases

EnsemblBacteriaiACO32749; ACO32749; ACP_1089.
GeneIDi7701016.
KEGGiaca:ACP_1089.
PATRICi20665531. VBIAciCap40988_1057.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001472 Genomic DNA. Translation: ACO32749.1 .
RefSeqi WP_015896247.1. NC_012483.1.
YP_002754194.1. NC_012483.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 240015.ACP_1089.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO32749 ; ACO32749 ; ACP_1089 .
GeneIDi 7701016.
KEGGi aca:ACP_1089.
PATRICi 20665531. VBIAciCap40988_1057.

Phylogenomic databases

eggNOGi COG0472.
HOGENOMi HOG000275122.
KOi K01000.
OMAi QIHYVSG.
OrthoDBi EOG69GZPZ.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci ACAP240015:GKF4-1067-MONOMER.

Family and domain databases

HAMAPi MF_00038. MraY.
InterProi IPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view ]
PANTHERi PTHR22926. PTHR22926. 1 hit.
Pfami PF00953. Glycos_transf_4. 1 hit.
PF10555. MraY_sig1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00445. mraY. 1 hit.
PROSITEi PS01348. MRAY_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51196 / DSM 11244 / JCM 7670.

Entry informationi

Entry nameiMRAY_ACIC5
AccessioniPrimary (citable) accession number: C1F461
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: September 3, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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