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Protein

DNA ligase

Gene

ACP_2652

Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciACAP240015:GKF4-2601-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:ACP_2652Imported
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)Imported
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
ProteomesiUP000002207 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi240015.ACP_2652.

Structurei

3D structure databases

ProteinModelPortaliC1F2J2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036008.
KOiK10747.
OMAiIEEFWQT.
OrthoDBiEOG6Q8HXT.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1F2J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRPAPQTSA PFDAFARCND ALAATPGKLA RREILVAYLR PLAVPDAARA
60 70 80 90 100
ASSVPPTLTL ADVEQAFAQI AAARGPAPRL QRVRQLLACA TPLEIKYLIK
110 120 130 140 150
LMLGDLRTGV KQALVEEAIA QLHEVELPTL RRALMLNGSL PEVVAMAAAH
160 170 180 190 200
TLPQAQMRLF HPLGFMLASP VAGVEEAMAR FASKPDARQA SEPPTAIQIE
210 220 230 240 250
DKYDGIRAQL HCGDPAQPGR VTLFSRNRED IGISFPELIE AFAAMPEPVV
260 270 280 290 300
LDGEILAWQP ASATGAARAM PFAALTQRLG RKRVTAQMRD QIPVVFMAFD
310 320 330 340 350
LLARHGELLL DQPLSSRRQQ LEAFLAAASP LALPAGAAQS SLFAAEESAD
360 370 380 390 400
FLRLKLAPAT QLESAAQLDR AYQDARARGN EGVMLKALAS PYQPGRRGLA
410 420 430 440 450
WLKLKRELAT LDVVVTGAEF GHGKRAHVLS DYTFAVRDGE ELKNIGKAYS
460 470 480 490 500
GLTDAEIAAN TKFLKEHTLE DFGHFRSVEP LLVLEVAFNN IQRSERHNSG
510 520 530 540
FALRFPRIVR IRDDKPVEEI DTLARVEELY QSQPDKPPEA
Length:540
Mass (Da):58,916
Last modified:May 25, 2009 - v1
Checksum:iA930EDCDC1CC8371
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA. Translation: ACO33334.1.
RefSeqiWP_015897717.1. NC_012483.1.
YP_002755673.1. NC_012483.1.

Genome annotation databases

EnsemblBacteriaiACO33334; ACO33334; ACP_2652.
KEGGiaca:ACP_2652.
PATRICi20668547. VBIAciCap40988_2537.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA. Translation: ACO33334.1.
RefSeqiWP_015897717.1. NC_012483.1.
YP_002755673.1. NC_012483.1.

3D structure databases

ProteinModelPortaliC1F2J2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240015.ACP_2652.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO33334; ACO33334; ACP_2652.
KEGGiaca:ACP_2652.
PATRICi20668547. VBIAciCap40988_2537.

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036008.
KOiK10747.
OMAiIEEFWQT.
OrthoDBiEOG6Q8HXT.

Enzyme and pathway databases

BioCyciACAP240015:GKF4-2601-MONOMER.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51196 / DSM 11244 / JCM 7670Imported.

Entry informationi

Entry nameiC1F2J2_ACIC5
AccessioniPrimary (citable) accession number: C1F2J2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 25, 2009
Last sequence update: May 25, 2009
Last modified: March 31, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.