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C1F2H8 (C1F2H8_ACIC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Acyl-(Acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase EMBL ACO32497.1
EC=2.3.1.129 EMBL ACO32497.1
Gene names
Name:lpxA EMBL ACO32497.1
Ordered Locus Names:ACP_2638
OrganismAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]
Taxonomic identifier240015 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. SAAS SAAS010137

Subunit structure

Homotrimer By similarity. SAAS SAAS010137

Subcellular location

Cytoplasm By similarity SAAS SAAS010137.

Ontologies

Keywords
   Biological processLipid A biosynthesis SAAS SAAS010137
Lipid synthesis
   Cellular componentCytoplasm SAAS SAAS010137
   DomainRepeat SAAS SAAS010137
   Molecular functionAcyltransferase SAAS SAAS010137 EMBL ACO32497.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlipid A biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionacyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
C1F2H8 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 8B99F095A3497508

FASTA25827,373
        10         20         30         40         50         60 
MSIHPTAIVA EGAVVPASCT VGPYCTIGPN VVLGEDCELA SHVVLDGHLT AGARNKFYSF 

        70         80         90        100        110        120 
ACVGIAPQDL KYKGEPTAVV LGDDNTIREY VTISRGTPGG GGATRVGSGC LIMAYTHIGH 

       130        140        150        160        170        180 
DSVIGNGCIL ANAATLAGHV IVEDYATVGA LCPVHQFCRI GRYAYIGGGT TITQDVLPFS 

       190        200        210        220        230        240 
LTSAKRETHA YGLNKVGLER RGFDRPRLRA IQHAYRLLLA AKMNTTQAIA KLREEGIATE 

       250 
DVAYLVEFIE QSERGVLK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001472 Genomic DNA. Translation: ACO32497.1.
RefSeqYP_002755659.1. NC_012483.1.

3D structure databases

ProteinModelPortalC1F2H8.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1F2H8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7700000.
GenomeReviewsGene locus ACP_2638 in contig CP001472_GR.
KEGGaca:ACP_2638.
PATRIC20668519. VBIAciCap40988_2523.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAREFCTFN.

Family and domain databases

InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 4 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC1F2H8_ACIC5
AccessionPrimary (citable) accession number: C1F2H8
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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