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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381SubstrateUniRule annotation
Binding sitei126 – 1261SubstrateUniRule annotation
Binding sitei159 – 1591SubstrateUniRule annotation
Binding sitei210 – 2101ATPUniRule annotation
Binding sitei333 – 3331ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi360 – 3634ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciACAP240015:GKF4-621-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:ACP_0631
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
ProteomesiUP000002207 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404Phosphoglycerate kinasePRO_1000192788Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi240015.ACP_0631.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate bindingUniRule annotation
Regioni61 – 644Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiFPVDYVT.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1F1M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLSIRDLD LAHKHVFMRV DFNVPLSEDG SEITDDTRIR ETLPTIEYAL
60 70 80 90 100
RHKAKLILAS HLGRPKGKVN PKYSLRPVVD RLRTLLDHDV TSRVNVAFSP
110 120 130 140 150
DCVGDVAKEL SLQLESGQVL LLENLRFHAE EEANDPEFAR KLASLCEIYV
160 170 180 190 200
NDAFGSAHRA HASTEGITHF VKQSAAGLLM EKELEYLGKA LEAPAKPFVA
210 220 230 240 250
IIGGAKVSDK IKVIDNLLNK VDALLIGGGM AYTFLKSQGQ DVGKSLVEAD
260 270 280 290 300
KLDIAKAALD KAKEKGVRFL LPVDHILADK FAADAATQTF EGTGAFPAEW
310 320 330 340 350
MALDIGPKSI ELFTKEIAAA DTIVWNGPMG VFEMPAFAKG TTAVAQAVAD
360 370 380 390 400
NVDAVSIIGG GDSVAAVKQA GVADKIKHIS TGGGASLEFL EGKKLPGVEA

LTEK
Length:404
Mass (Da):43,360
Last modified:May 26, 2009 - v1
Checksum:i1D33462F3993D0CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA. Translation: ACO34607.1.
RefSeqiYP_002753758.1. NC_012483.1.

Genome annotation databases

EnsemblBacteriaiACO34607; ACO34607; ACP_0631.
KEGGiaca:ACP_0631.
PATRICi20664635. VBIAciCap40988_0612.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA. Translation: ACO34607.1.
RefSeqiYP_002753758.1. NC_012483.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240015.ACP_0631.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO34607; ACO34607; ACP_0631.
KEGGiaca:ACP_0631.
PATRICi20664635. VBIAciCap40988_0612.

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiFPVDYVT.
OrthoDBiEOG64N9Z0.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.
BioCyciACAP240015:GKF4-621-MONOMER.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51196 / DSM 11244 / JCM 7670.

Entry informationi

Entry nameiPGK_ACIC5
AccessioniPrimary (citable) accession number: C1F1M9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: April 1, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.