Skip Header

Contribute Send feedback
Read comments (?) or add your own

C1F1C6 (C1F1C6_ACIC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Uroporphyrinogen decarboxylase HAMAP MF_00218
Short name=UPD HAMAP MF_00218
Short name=URO-D HAMAP MF_00218
EC=4.1.1.37 HAMAP MF_00218
Gene names
Name:hemE HAMAP MF_00218 EMBL ACO32887.1
Ordered Locus Names:ACP_2432
OrganismAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670) [Complete proteome] [HAMAP]
Taxonomic identifier240015 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Acidobacterium

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III By similarity. HAMAP MF_00218 SAAS SAAS006361

Catalytic activity

Uroporphyrinogen III = coproporphyrinogen + 4 CO2. HAMAP MF_00218 RuleBase RU000554 SAAS SAAS006361

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen III from 5-aminolevulinate: step 4/4. RuleBase RU000554

Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4. HAMAP MF_00218 SAAS SAAS006361

Subunit structure

Homodimer By similarity. HAMAP MF_00218 SAAS SAAS006361

Subcellular location

Cytoplasm By similarity HAMAP MF_00218 SAAS SAAS006361.

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family. HAMAP MF_00218 RuleBase RU004169

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region42 – 465Substrate binding By similarity HAMAP MF_00218

Sites

Binding site911Substrate By similarity HAMAP MF_00218
Binding site1671Substrate By similarity HAMAP MF_00218
Binding site2221Substrate By similarity HAMAP MF_00218
Binding site3361Substrate By similarity HAMAP MF_00218
Site911Transition state stabilizer By similarity HAMAP MF_00218

Sequences

Sequence LengthMass (Da)Tools
C1F1C6 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 54D59128957F7E63

FASTA36240,329
        10         20         30         40         50         60 
MPLNPENGAL AADALSLSAH GGRFVRACLR RPVDRTPVWF LRQAGRYMPE YMAVRKHHSL 

        70         80         90        100        110        120 
LDICKRPEIA AEVTITAAEK LDVDAAIIFA DLLLPFECMG LPFEFQAGEG PVVHHPVRTL 

       130        140        150        160        170        180 
EDVERLRTDK ASELIYVAQA IEKVVAHFKD RLGIIGFCGA PYTLASYMIE GGGTRQYIET 

       190        200        210        220        230        240 
KKFMYRQPDA WKQLLDKLVT VLTAYARQQV EAGADVIQIF DSWAGSLSVE DYREFVLPVT 

       250        260        270        280        290        300 
RQLVREVQAL GVPVIYFGVD TASLLPSMRE TGADVLGLDW RTPLAEAWHR LDYGCAVQGN 

       310        320        330        340        350        360 
LDPITLFAEP DLIRNRVENI LAQAANRPGH IFNLGHGIVP GTPVEHVQAV VKFVREYKPA 


TL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001472 Genomic DNA. Translation: ACO32887.1.
RefSeqYP_002755470.1. NC_012483.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC1F1C6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7699737.
GenomeReviewsGene locus ACP_2432 in contig CP001472_GR.
KEGGaca:ACP_2432.
PATRIC20668113. VBIAciCap40988_2330.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAPRIHFGV.
ProtClustDBCLSK2467472.

Family and domain databases

HAMAPMF_00218. URO_D.
[Tree]
InterProIPR006361. Uroporphyrinogen_deCO2ase_HemE.
IPR000257. Uroporphyrinogen_deCOase.
[Graphical view]
KOK01599.
PANTHERPTHR21091:SF2. HemE. 1 hit.
PfamPF01208. URO-D. 1 hit.
[Graphical view]
TIGRFAMsTIGR01464. HemE. 1 hit.
PROSITEPS00906. UROD_1. 1 hit.
PS00907. UROD_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1F1C6_ACIC5
AccessionPrimary (citable) accession number: C1F1C6
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info