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Protein

Chaperone protein ClpB

Gene

clpB

Organism
Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation
Biological processStress responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciACAP240015:G1GV4-2292-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein ClpBUniRule annotation
Gene namesi
Name:clpBUniRule annotationImported
Ordered Locus Names:ACP_2407Imported
OrganismiAcidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)Imported
Taxonomic identifieri240015 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
Proteomesi
  • UP000002207 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homohexamer. The oligomerization is ATP-dependent.SAAS annotation
Homohexamer; The oligomerization is ATP-dependent.UniRule annotation

Protein-protein interaction databases

STRINGi240015.ACP_2407

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini201 – 347AAAInterPro annotationAdd BLAST147
Domaini603 – 756AAAInterPro annotationAdd BLAST154
Domaini774 – 865ClpB_D2-smallInterPro annotationAdd BLAST92

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili437 – 464UniRule annotationAdd BLAST28
Coiled coili468 – 495UniRule annotationAdd BLAST28
Coiled coili509 – 539UniRule annotationAdd BLAST31

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilUniRule annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C2Z Bacteria
COG0542 LUCA
HOGENOMiHOG000218211
KOiK03695
OMAiHHKVRIK
OrthoDBiPOG091H019M

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR017730 Chaperonin_ClpB
IPR019489 Clp_ATPase_C
IPR004176 Clp_N
IPR036628 Clp_N_dom_sf
IPR001270 ClpA/B
IPR018368 ClpA/B_CS1
IPR028299 ClpA/B_CS2
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF07724 AAA_2, 1 hit
PF02861 Clp_N, 2 hits
PF10431 ClpB_D2-small, 1 hit
PRINTSiPR00300 CLPPROTEASEA
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01086 ClpB_D2-small, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
SSF81923 SSF81923, 1 hit
TIGRFAMsiTIGR03346 chaperone_ClpB, 1 hit
PROSITEiView protein in PROSITE
PS00870 CLPAB_1, 1 hit
PS00871 CLPAB_2, 1 hit

Sequencei

Sequence statusi: Complete.

C1F1A3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIRWDKFTV KSQEAVQAAS GIASEHGNPE LLTLHLLAAL LADQESIVVP
60 70 80 90 100
VLEKVGVPTA QLRTKVEEAI AKLPKVSGAS AQPGIAATLN KVFDQAFKEA
110 120 130 140 150
ENFKDDYVST EHLLLAMAAQ KNDGAQLLLA SVGATYDAIL KSLSSVRGSQ
160 170 180 190 200
RVTDQNPEGK FQALEKYAKD LTELARRGKL DPVIGRDEEI RRVVQVLSRR
210 220 230 240 250
TKNNPVLIGE PGVGKTAIVE GLARRIVHGD VPEILREKRV ISLDLGSMLA
260 270 280 290 300
GAKFRGEFED RLKAVLKEIE ESNGQIILFI DELHTLVGAG AAEGAIDASN
310 320 330 340 350
MLKPALARGE LRAIGATTLN EYRKYIEKDA ALERRFQIVF VGEPNVEDTI
360 370 380 390 400
AILRGLKERY EAHHKVRIKD AAIVSAATLS HRYISDRFLP DKAIDLVDEA
410 420 430 440 450
AASLAIQIGS VPTEIDQLER EATSLEIERT ALKRETDQNS KDRLEVVERE
460 470 480 490 500
LAALKEQATG LRARWQKERE AITQLSELKN RVEALRFEAD EQTRRGNLER
510 520 530 540 550
AAQIQYGELP RLEAEVQKLN AQQEGAENAQ RMLKEEVDEE DIARVVSKWT
560 570 580 590 600
GIPVAKMLEG EVQKLVQMEE RLRDRVVGQD EALSTVANAI RRSRAGLSDP
610 620 630 640 650
KRPIGSFIFL GPTGVGKTET ARALAEFLFD DEQAMIRIDM SEYMEKHAVA
660 670 680 690 700
RLIGAPPGYV GYDEGGQLTE AVRRRPYSVV LFDEIEKAHP DVFNVLLQVL
710 720 730 740 750
DDGRLTDSKG RTVDFKNTVL IMTSNLGAQA LHAEALQDEA AFEQAREQVM
760 770 780 790 800
EVLRQSFRPE FLNRVDDIVI FRPLGEAQLV HIVDLRLKDL EQLLKERHIT
810 820 830 840 850
IELTDAARHQ LFLSGYDRAY GARPLKRAMQ RLIQDPLAMR ILDGEVLHGD
860 870
HVRIDADPLK NQLSFEVTGR EAVK
Length:874
Mass (Da):97,364
Last modified:May 26, 2009 - v1
Checksum:i0A9EDE3E22A1639F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001472 Genomic DNA Translation: ACO32383.1
RefSeqiWP_015897493.1, NC_012483.1

Genome annotation databases

EnsemblBacteriaiACO32383; ACO32383; ACP_2407
KEGGiaca:ACP_2407

Similar proteinsi

Entry informationi

Entry nameiC1F1A3_ACIC5
AccessioniPrimary (citable) accession number: C1F1A3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health