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Protein

8-amino-7-oxononanoate synthase

Gene

bioF

Organism
Bacillus cereus (strain 03BB102)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein].SAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. 8-amino-7-oxononanoate synthase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. biotin biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Keywords - Biological processi

Biotin biosynthesisSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBCER572264:GH22-4166-MONOMER.
UniPathwayiUPA00078.

Names & Taxonomyi

Protein namesi
Recommended name:
8-amino-7-oxononanoate synthaseSAAS annotation (EC:2.3.1.47SAAS annotation)
Gene namesi
Name:bioFImported
Ordered Locus Names:BCA_4230Imported
OrganismiBacillus cereus (strain 03BB102)Imported
Taxonomic identifieri572264 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000002210: Chromosome

Interactioni

Subunit structurei

Homodimer.SAAS annotation

Protein-protein interaction databases

STRINGi572264.BCA_4230.

Structurei

3D structure databases

ProteinModelPortaliC1EQZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0156.
HOGENOMiHOG000221021.
KOiK00652.
OMAiRFTHNDP.
OrthoDBiEOG6Q8HZD.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR004723. AONS_Archaea/Proteobacteria.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00858. bioF. 1 hit.
PROSITEiPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1EQZ1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNQPWRTHLQ TKLQQLHEQG QYRNLHVTEQ AEETWLIRDE KRMLNLASNN
60 70 80 90 100
YLGLAGDERL KEAAIVCTRK YGTGATASRL VVGNYSLYEE VERSICNWKG
110 120 130 140 150
TEKALVVNSG FTANVGAISS LACRHDIVFS DKLNHASIVD GIILSGAEHK
160 170 180 190 200
RYRHNDLNHL EVLLKTASPE KRKLIVTDTV FSMDGDTAYL RELVQLKEKY
210 220 230 240 250
GAIIIVDEAH ASGIYGIGGA GLSHIEKDLA QKIDIHMGTF SKALGCYGAY
260 270 280 290 300
LTGDAIYIEY LQNMMRSFIF TTALPPSTLG AVQKAIEIVQ EDHKRRENLI
310 320 330 340 350
ANGEYFRSKL REAGFNIGNS STHIVPIVVG SNENTLRFSK RLQEAGIAAI
360 370 380 390
AIRPPTVPVH SSRIRFAVTS QHTIADLKWA IDRITHIAKE EELFV
Length:395
Mass (Da):44,126
Last modified:May 26, 2009 - v1
Checksum:i09A0262EC8BFABD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001407 Genomic DNA. Translation: ACO26546.1.
RefSeqiYP_002751481.1. NC_012472.1.

Genome annotation databases

EnsemblBacteriaiACO26546; ACO26546; BCA_4230.
GeneIDi7689425.
KEGGibcx:BCA_4230.
PATRICi18821611. VBIBacCer84800_4121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001407 Genomic DNA. Translation: ACO26546.1.
RefSeqiYP_002751481.1. NC_012472.1.

3D structure databases

ProteinModelPortaliC1EQZ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi572264.BCA_4230.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO26546; ACO26546; BCA_4230.
GeneIDi7689425.
KEGGibcx:BCA_4230.
PATRICi18821611. VBIBacCer84800_4121.

Phylogenomic databases

eggNOGiCOG0156.
HOGENOMiHOG000221021.
KOiK00652.
OMAiRFTHNDP.
OrthoDBiEOG6Q8HZD.

Enzyme and pathway databases

UniPathwayiUPA00078.
BioCyciBCER572264:GH22-4166-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR004723. AONS_Archaea/Proteobacteria.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00858. bioF. 1 hit.
PROSITEiPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Bacillus cereus 03BB102."
    Dodson R.J., Jackson P., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C., Sutton G., Sims D.
    Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 03BB102Imported.

Entry informationi

Entry nameiC1EQZ1_BACC3
AccessioniPrimary (citable) accession number: C1EQZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: February 4, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.