Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C1EPL6

- ILVD_BACC3

UniProt

C1EPL6 - ILVD_BACC3

Protein

Dihydroxy-acid dehydratase

Gene

ilvD

Organism
Bacillus cereus (strain 03BB102)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.UniRule annotation

    Cofactori

    Binds 1 4Fe-4S cluster.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi119 – 1191Iron-sulfur (4Fe-4S)UniRule annotation
    Metal bindingi192 – 1921Iron-sulfur (4Fe-4S)UniRule annotation

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. dihydroxy-acid dehydratase activity Source: UniProtKB-HAMAP
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. isoleucine biosynthetic process Source: UniProtKB-HAMAP
    2. valine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Branched-chain amino acid biosynthesis

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding

    Enzyme and pathway databases

    BioCyciBCER572264:GH22-1817-MONOMER.
    UniPathwayiUPA00047; UER00057.
    UPA00049; UER00061.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Dihydroxy-acid dehydrataseUniRule annotation (EC:4.2.1.9UniRule annotation)
    Short name:
    DADUniRule annotation
    Gene namesi
    Name:ilvDUniRule annotation
    Ordered Locus Names:BCA_1859
    OrganismiBacillus cereus (strain 03BB102)
    Taxonomic identifieri572264 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000002210: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 557557Dihydroxy-acid dehydratasePRO_1000116499Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi572264.BCA_1859.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the IlvD/Edd family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0129.
    HOGENOMiHOG000173155.
    KOiK01687.
    OMAiYAALTTN.
    OrthoDBiEOG6MSS24.

    Family and domain databases

    HAMAPiMF_00012. IlvD.
    InterProiIPR015928. Aconitase/3IPM_dehydase_swvl.
    IPR004404. DihydroxyA_deHydtase.
    IPR000581. DiOHA_6PGluconate_deHydtase.
    IPR020558. DiOHA_6PGluconate_deHydtase_CS.
    [Graphical view]
    PANTHERiPTHR21000. PTHR21000. 1 hit.
    PfamiPF00920. ILVD_EDD. 1 hit.
    [Graphical view]
    SUPFAMiSSF52016. SSF52016. 1 hit.
    TIGRFAMsiTIGR00110. ilvD. 1 hit.
    PROSITEiPS00886. ILVD_EDD_1. 1 hit.
    PS00887. ILVD_EDD_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C1EPL6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRSDMIKKGF DKAPHRSLLK ATGLKDEDFD KPFIAICNSF IEIIPGHKHL    50
    NEFGKLVKEA VRAAGMVPFE FNTIGVDDGI AMGHIGMRYS LPSREIIADS 100
    VETVVNAHWF DGMICIPNCD KITPGMMMAA LRINIPTVFV SGGPMAAGKT 150
    SKGDVVDLSS VFEGVGAYQS GKISEEELKD IEDHGCPSCG SCSGMFTANS 200
    MNCLCEVLGL ALPGNGSILA IDPRREELIK QAAEKLKILI ERDIKPRDIV 250
    TEEAIDDAFA LDMAMGGSTN TVLHTLALAQ EAGLDYDMNR IDAVSRRVPH 300
    LCKVSPASNW HMEDIDRAGG ISAILKEMSR KEGVLHLDRI TATGQTLREN 350
    IAHAEIKDKE VIHSLENPHS EEGGLRILKG NLAKDGAVIK SGATEVKRFE 400
    GPCVIFNSQD EALAGIMLGK VKKGDVVVIR YEGPRGGPGM PEMLAPTSAI 450
    AGMGLGADVA LLTDGRFSGA SRGISVGHIS PEAAAGGTIA LLEQGDIVCI 500
    DVEERLLEVR VSDEELDKRK KEWKRPEPKV KTGWLGRYAQ MVTSANTGAV 550
    LKIPNFD 557
    Length:557
    Mass (Da):59,992
    Last modified:May 26, 2009 - v1
    Checksum:i39AACA4DC2C3C30B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001407 Genomic DNA. Translation: ACO26410.1.
    RefSeqiYP_002749134.1. NC_012472.1.

    Genome annotation databases

    EnsemblBacteriaiACO26410; ACO26410; BCA_1859.
    GeneIDi7689742.
    KEGGibcx:BCA_1859.
    PATRICi18816839. VBIBacCer84800_1736.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001407 Genomic DNA. Translation: ACO26410.1 .
    RefSeqi YP_002749134.1. NC_012472.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 572264.BCA_1859.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO26410 ; ACO26410 ; BCA_1859 .
    GeneIDi 7689742.
    KEGGi bcx:BCA_1859.
    PATRICi 18816839. VBIBacCer84800_1736.

    Phylogenomic databases

    eggNOGi COG0129.
    HOGENOMi HOG000173155.
    KOi K01687.
    OMAi YAALTTN.
    OrthoDBi EOG6MSS24.

    Enzyme and pathway databases

    UniPathwayi UPA00047 ; UER00057 .
    UPA00049 ; UER00061 .
    BioCyci BCER572264:GH22-1817-MONOMER.

    Family and domain databases

    HAMAPi MF_00012. IlvD.
    InterProi IPR015928. Aconitase/3IPM_dehydase_swvl.
    IPR004404. DihydroxyA_deHydtase.
    IPR000581. DiOHA_6PGluconate_deHydtase.
    IPR020558. DiOHA_6PGluconate_deHydtase_CS.
    [Graphical view ]
    PANTHERi PTHR21000. PTHR21000. 1 hit.
    Pfami PF00920. ILVD_EDD. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52016. SSF52016. 1 hit.
    TIGRFAMsi TIGR00110. ilvD. 1 hit.
    PROSITEi PS00886. ILVD_EDD_1. 1 hit.
    PS00887. ILVD_EDD_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Bacillus cereus 03BB102."
      Dodson R.J., Jackson P., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C., Sutton G., Sims D.
      Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 03BB102.

    Entry informationi

    Entry nameiILVD_BACC3
    AccessioniPrimary (citable) accession number: C1EPL6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3