C1EPG6 (C1EPG6_BACC3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Malate oxidoreductase (Oxaloacetate-decarboxylating) EMBL ACO29382.1
EC=1.1.1.38 EMBL ACO29382.1

Gene names

Name:	malS EMBL ACO29382.1
Ordered Locus Names:	BCA_1808 EMBL ACO29382.1

Organism

Bacillus cereus (strain 03BB102) [Complete proteome] [HAMAP] EMBL ACO29382.1

Taxonomic identifier

572264 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus cereus

Protein attributes

Sequence length	570 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Divalent metal cations. Prefers magnesium or manganese By similarity. PIRSR PIRSR000106-3
Sequence similarities	Belongs to the malic enzymes family. RuleBase RU003427

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003427 PIRSR PIRSR000106-3
Molecular function	Oxidoreductase RuleBase RU003427 EMBL ACO29382.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	malate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	NAD binding Inferred from electronic annotation. Source: InterPro malate dehydrogenase (oxaloacetate-decarboxylating) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	105	1	Proton donor By similarity PIRSR PIRSR000106-1
	Active site	178	1	Proton acceptor By similarity PIRSR PIRSR000106-1
	Metal binding	249	1	Divalent metal cation By similarity PIRSR PIRSR000106-3
	Metal binding	250	1	Divalent metal cation By similarity PIRSR PIRSR000106-3
	Metal binding	273	1	Divalent metal cation By similarity PIRSR PIRSR000106-3

Sequences

	Sequence		Length	Mass (Da)
	C1EPG6 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 8F19CF19FC777689	FASTA	570	62,244
	10 20 30 40 50 60 MSKFTVASNG SLETTLRGVE VLSTPLLNKG VAFTQEEREE LGLKGLLPPA VLTLEEQARR 70 80 90 100 110 120 AYEQFCSQPD DLLKNVYLTA LHDRNEVLFY RILTDHLREM LPIVYTPTVG VAIQRYSHEY 130 140 150 160 170 180 RKPRGVYLSI NDPSGIEEAF ANIGATAENI DLVVVTDGEG ILGIGDWGVG GINIAIGKLA 190 200 210 220 230 240 VYTAAVGIDP SRVLPVILDV GTNREELLNN PFYIGNRHPR ITGEAYDEFI DTFVQAVNKQ 250 260 270 280 290 300 FPKALLHWED FSSRNARKIL DKYRHDICTF NDDIQGTGAV SLAAVLSAVK ASGVPLSEHR 310 320 330 340 350 360 VVVFGAGTAG IGIADQVRDA MVRVGVSEEE SYKRFWCIDR NGLVTDNMED LLDFQMPYAR 370 380 390 400 410 420 KEAEVSEWKE NGVIGLAEVV KHVKPTILIG TSTVAGAFKE EIIKEMASHV ERPIILPMSN 430 440 450 460 470 480 PTPLAEAKPA DLIEWTEGRA LVATGSPFEP VTYNGVTYVI GQSNNALIFP GLGLGTIVVR 490 500 510 520 530 540 ASVMTDGMFA AAAEAVASMV DTSQPGAPIL PEVEELRNIS EMVAIEVAKI AVAEGVAREN 550 560 570 LSDNDIKIAV KEAIWEPEYR QIKAVEKVTI

References

[1]	"Genome sequence of Bacillus cereus 03BB102." Dodson R.J., Jackson P., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C., Sutton G., Sims D. Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 03BB102 EMBL ACO29382.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001407 Genomic DNA. Translation: ACO29382.1.
RefSeq	YP_002749084.1. NC_012472.1.
3D structure databases
ProteinModelPortal	C1EPG6.
ModBase	Search...
Protein-protein interaction databases
STRING	572264.BCA_1808.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACO29382; ACO29382; BCA_1808.
GeneID	7692437.
KEGG	bcx:BCA_1808.
PATRIC	18816735. VBIBacCer84800_1684.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0281.
HOGENOM	HOG000042487.
KO	K00027.
OMA	LASWYPE.
ProtClustDB	PRK13529.
Enzyme and pathway databases
BioCyc	BCER572264:GH22-3743-MONOMER.
Family and domain databases
Gene3D	3.40.50.10380. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR015884. Malic_enzyme_CS. IPR012301. Malic_N. IPR012302. Malic_NAD-bd. IPR001891. Malic_OxRdtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00390. malic. 1 hit. PF03949. Malic_M. 1 hit. [Graphical view]
PIRSF	PIRSF000106. ME. 1 hit.
PRINTS	PR00072. MALOXRDTASE.
SMART	SM00919. Malic_M. 1 hit. [Graphical view]
PROSITE	PS00331. MALIC_ENZYMES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1EPG6_BACC3

Accession

Primary (citable) accession number: C1EPG6

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)