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C1EPG6

- C1EPG6_BACC3

UniProt

C1EPG6 - C1EPG6_BACC3

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Protein
Submitted name:

Malate oxidoreductase (Oxaloacetate-decarboxylating)

Gene

malS

Organism
Bacillus cereus (strain 03BB102)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Cofactori

Divalent metal cations. Prefers magnesium or manganese.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei105 – 1051Proton donorUniRule annotation
Active sitei178 – 1781Proton acceptorUniRule annotation
Metal bindingi249 – 2491Divalent metal cation
Metal bindingi250 – 2501Divalent metal cation
Metal bindingi273 – 2731Divalent metal cation

GO - Molecular functioni

  1. malate dehydrogenase (decarboxylating) (NAD+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
  3. NAD binding Source: InterPro
  4. oxaloacetate decarboxylase activity Source: UniProtKB-EC

GO - Biological processi

  1. malate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBCER572264:GH22-1767-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Malate oxidoreductase (Oxaloacetate-decarboxylating)Imported (EC:1.1.1.38Imported)
Gene namesi
Name:malSImported
Ordered Locus Names:BCA_1808Imported
OrganismiBacillus cereus (strain 03BB102)Imported
Taxonomic identifieri572264 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000002210: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi572264.BCA_1808.

Structurei

3D structure databases

ProteinModelPortaliC1EPG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the malic enzymes family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0281.
HOGENOMiHOG000042487.
KOiK00027.
OMAiDAQKPYA.
OrthoDBiEOG6QVRGM.

Family and domain databases

Gene3Di3.40.50.10380. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR015884. Malic_enzyme_CS.
IPR012301. Malic_N_dom.
IPR012302. Malic_NAD-bd.
IPR001891. Malic_OxRdtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00390. malic. 1 hit.
PF03949. Malic_M. 1 hit.
[Graphical view]
PIRSFiPIRSF000106. ME. 1 hit.
PRINTSiPR00072. MALOXRDTASE.
SMARTiSM00919. Malic_M. 1 hit.
[Graphical view]
PROSITEiPS00331. MALIC_ENZYMES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1EPG6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKFTVASNG SLETTLRGVE VLSTPLLNKG VAFTQEEREE LGLKGLLPPA
60 70 80 90 100
VLTLEEQARR AYEQFCSQPD DLLKNVYLTA LHDRNEVLFY RILTDHLREM
110 120 130 140 150
LPIVYTPTVG VAIQRYSHEY RKPRGVYLSI NDPSGIEEAF ANIGATAENI
160 170 180 190 200
DLVVVTDGEG ILGIGDWGVG GINIAIGKLA VYTAAVGIDP SRVLPVILDV
210 220 230 240 250
GTNREELLNN PFYIGNRHPR ITGEAYDEFI DTFVQAVNKQ FPKALLHWED
260 270 280 290 300
FSSRNARKIL DKYRHDICTF NDDIQGTGAV SLAAVLSAVK ASGVPLSEHR
310 320 330 340 350
VVVFGAGTAG IGIADQVRDA MVRVGVSEEE SYKRFWCIDR NGLVTDNMED
360 370 380 390 400
LLDFQMPYAR KEAEVSEWKE NGVIGLAEVV KHVKPTILIG TSTVAGAFKE
410 420 430 440 450
EIIKEMASHV ERPIILPMSN PTPLAEAKPA DLIEWTEGRA LVATGSPFEP
460 470 480 490 500
VTYNGVTYVI GQSNNALIFP GLGLGTIVVR ASVMTDGMFA AAAEAVASMV
510 520 530 540 550
DTSQPGAPIL PEVEELRNIS EMVAIEVAKI AVAEGVAREN LSDNDIKIAV
560 570
KEAIWEPEYR QIKAVEKVTI
Length:570
Mass (Da):62,244
Last modified:May 26, 2009 - v1
Checksum:i8F19CF19FC777689
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001407 Genomic DNA. Translation: ACO29382.1.
RefSeqiWP_012680302.1. NC_012472.1.
YP_002749084.1. NC_012472.1.

Genome annotation databases

EnsemblBacteriaiACO29382; ACO29382; BCA_1808.
GeneIDi7692437.
KEGGibcx:BCA_1808.
PATRICi18816735. VBIBacCer84800_1684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001407 Genomic DNA. Translation: ACO29382.1 .
RefSeqi WP_012680302.1. NC_012472.1.
YP_002749084.1. NC_012472.1.

3D structure databases

ProteinModelPortali C1EPG6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 572264.BCA_1808.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO29382 ; ACO29382 ; BCA_1808 .
GeneIDi 7692437.
KEGGi bcx:BCA_1808.
PATRICi 18816735. VBIBacCer84800_1684.

Phylogenomic databases

eggNOGi COG0281.
HOGENOMi HOG000042487.
KOi K00027.
OMAi DAQKPYA.
OrthoDBi EOG6QVRGM.

Enzyme and pathway databases

BioCyci BCER572264:GH22-1767-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10380. 1 hit.
3.40.50.720. 1 hit.
InterProi IPR015884. Malic_enzyme_CS.
IPR012301. Malic_N_dom.
IPR012302. Malic_NAD-bd.
IPR001891. Malic_OxRdtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00390. malic. 1 hit.
PF03949. Malic_M. 1 hit.
[Graphical view ]
PIRSFi PIRSF000106. ME. 1 hit.
PRINTSi PR00072. MALOXRDTASE.
SMARTi SM00919. Malic_M. 1 hit.
[Graphical view ]
PROSITEi PS00331. MALIC_ENZYMES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Bacillus cereus 03BB102."
    Dodson R.J., Jackson P., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C., Sutton G., Sims D.
    Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 03BB102Imported.

Entry informationi

Entry nameiC1EPG6_BACC3
AccessioniPrimary (citable) accession number: C1EPG6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3