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Protein

Signal peptidase I

Gene

sipT

Organism
Bacillus cereus (strain 03BB102)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.UniRule annotation

GO - Molecular functioni

  1. serine-type peptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseUniRule annotation

Enzyme and pathway databases

BioCyciBCER572264:GH22-1148-MONOMER.

Protein family/group databases

MEROPSiS26.018.

Names & Taxonomyi

Protein namesi
Recommended name:
Signal peptidase IUniRule annotation (EC:3.4.21.89UniRule annotation)
Gene namesi
Name:sipTImported
Synonyms:lepBImported
Ordered Locus Names:BCA_1180Imported
ORF Names:AS54_1221Imported
OrganismiBacillus cereus (strain 03BB102)Imported
Taxonomic identifieri572264 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000002210 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi572264.BCA_1180.

Structurei

3D structure databases

ProteinModelPortaliC1EKR0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S26 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0681.
HOGENOMiHOG000003673.
KOiK03100.
OMAiTNINTMA.
OrthoDBiEOG622PW8.

Family and domain databases

Gene3Di2.10.109.10. 2 hits.
InterProiIPR000223. Pept_S26A_signal_pept_1.
IPR019758. Pept_S26A_signal_pept_1_CS.
IPR019757. Pept_S26A_signal_pept_1_Lys-AS.
IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
IPR028360. Peptidase_S24/S26_b-rbn.
IPR019759. Peptidase_S24_S26.
IPR015927. Peptidase_S24_S26A/B/C.
[Graphical view]
PANTHERiPTHR12383. PTHR12383. 1 hit.
PfamiPF00717. Peptidase_S24. 1 hit.
[Graphical view]
PRINTSiPR00727. LEADERPTASE.
SUPFAMiSSF51306. SSF51306. 1 hit.
TIGRFAMsiTIGR02227. sigpep_I_bact. 1 hit.
PROSITEiPS00501. SPASE_I_1. 1 hit.
PS00760. SPASE_I_2. 1 hit.
PS00761. SPASE_I_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1EKR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTLKKEGI EWIRTILIGV LLAVFFRTFF FSTYVVEGKS MMPTLQDGNM
60 70 80 90 100
LVVNKVSYHV GDLNRFDVVV FHANKKEDYV KRIIGLPGDH IEYKHDKLYV
110 120 130 140 150
NGQFVDEPYL ETYKKEIDGR QLTGDFKLEE LTKEKSVPPG YIFVVGDNRL
160 170 180
GSWDSRHFGF VKADTVVGKV DLRYWPIQDV QTNFSKG
Length:187
Mass (Da):21,664
Last modified:May 26, 2009 - v1
Checksum:i8B028BD9CF6D3875
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001407 Genomic DNA. Translation: ACO26409.1.
CP009318 Genomic DNA. Translation: AJG54227.1.
RefSeqiYP_002748469.1. NC_012472.1.

Genome annotation databases

EnsemblBacteriaiACO26409; ACO26409; BCA_1180.
KEGGibcx:BCA_1180.
PATRICi18815487. VBIBacCer84800_1061.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001407 Genomic DNA. Translation: ACO26409.1.
CP009318 Genomic DNA. Translation: AJG54227.1.
RefSeqiYP_002748469.1. NC_012472.1.

3D structure databases

ProteinModelPortaliC1EKR0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi572264.BCA_1180.

Protein family/group databases

MEROPSiS26.018.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO26409; ACO26409; BCA_1180.
KEGGibcx:BCA_1180.
PATRICi18815487. VBIBacCer84800_1061.

Phylogenomic databases

eggNOGiCOG0681.
HOGENOMiHOG000003673.
KOiK03100.
OMAiTNINTMA.
OrthoDBiEOG622PW8.

Enzyme and pathway databases

BioCyciBCER572264:GH22-1148-MONOMER.

Family and domain databases

Gene3Di2.10.109.10. 2 hits.
InterProiIPR000223. Pept_S26A_signal_pept_1.
IPR019758. Pept_S26A_signal_pept_1_CS.
IPR019757. Pept_S26A_signal_pept_1_Lys-AS.
IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
IPR028360. Peptidase_S24/S26_b-rbn.
IPR019759. Peptidase_S24_S26.
IPR015927. Peptidase_S24_S26A/B/C.
[Graphical view]
PANTHERiPTHR12383. PTHR12383. 1 hit.
PfamiPF00717. Peptidase_S24. 1 hit.
[Graphical view]
PRINTSiPR00727. LEADERPTASE.
SUPFAMiSSF51306. SSF51306. 1 hit.
TIGRFAMsiTIGR02227. sigpep_I_bact. 1 hit.
PROSITEiPS00501. SPASE_I_1. 1 hit.
PS00760. SPASE_I_2. 1 hit.
PS00761. SPASE_I_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of Bacillus cereus 03BB102."
    Dodson R.J., Jackson P., Munk A.C., Brettin T., Bruce D., Detter C., Tapia R., Han C., Sutton G., Sims D.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 03BB102Imported.
  2. Bidwell S., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 03BB102Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 03BB102Imported.

Entry informationi

Entry nameiC1EKR0_BACC3
AccessioniPrimary (citable) accession number: C1EKR0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: April 1, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.