AMY1

Functionⁱ

Catalytic activityⁱ

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functionⁱ

alpha-amylase activity Source: UniProtKB-UniRule
calcium ion binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

carbohydrate metabolic process Source: UniProtKB-KW

Complete GO annotation...

Keywordsⁱ

Molecular function	GlycosidaseUniRule annotation, Hydrolase
Biological process	Carbohydrate metabolismUniRule annotation

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GH13. Glycoside Hydrolase Family 13.

CAZyⁱ

GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesⁱ	Name:AMY1Imported ORF Names:MICPUN_96728Imported
Organismⁱ	Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic green alga)Imported
Taxonomic identifierⁱ	296587 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Chlorophyta › prasinophytes › Mamiellophyceae › Mamiellales › Mamiellaceae › Micromonas
Proteomesⁱ	UP000002009 Componentⁱ: Chromosome 14

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C1EGI4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 320	AamyInterPro annotationAdd BLAST		320
Domainⁱ	321 – 384	Alpha-amyl_C2InterPro annotationAdd BLAST		64

Sequence similaritiesⁱ

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

HOGENOMⁱ	HOG000239525.
InParanoidⁱ	C1EGI4.
KEGG Orthology (KO) More...KOⁱ	K01176.

Family and domain databases

InterProⁱ	View protein in InterPro IPR012850. A-amylase_bs_C. IPR006046. Alpha_amylase. IPR006047. Glyco_hydro_13_cat_dom. IPR017853. Glycoside_hydrolase_SF.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07821. Alpha-amyl_C2. 1 hit. PF00128. Alpha-amylase. 1 hit.
PRINTSⁱ	PR00110. ALPHAAMYLASE.
SMARTⁱ	View protein in SMART SM00642. Aamy. 1 hit. SM00810. Alpha-amyl_C2. 1 hit.
SUPFAMⁱ	SSF51445. SSF51445. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

C1EGI4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVPDIAATGV THLWLPPPSH SVSPEGYLPR HLWNLDSSEY GDQNELVALN 
        60         70         80         90        100
ASLREAGIMP VCDVVINHRT ADEIGPEGVY NVYSDEVDHT GTAVHWGRHM 
       110        120        130        140        150
ITCNDPAFHG SGHEDSGDNY DAAPDLDHAN DELRATLKRW LRWLRWDVGF 
       160        170        180        190        200
GGFRFDFVRG YAPEYTEEYV KETTSRGDFC VGENWVDLAW EGSHLNYNQD 
       210        220        230        240        250
GPRGKLVEWL AATHGTCALF DFPTKGILQR AVTHVEFYRL RDPASRPPGL 
       260        270        280        290        300
SGWIPSRAVT FVDNHDTGAP QNHWPFPPDR IALGYAYVLT HPGIPCVFGP 
       310        320        330        340        350
HLWGDDPVLS GVIRLLIDLR KRCCVCADAP VKIQMAENDI YVAKVGHRLT 
       360        370        380        390        400
VKLGPRYEMP VELIPKEPEW SLAVAGEDYA VWERVQYDTD ADAKVVAMER 
       410        420        430        440 
EMMDVGDDGE YYPLERVPVD NSRQSIGSWI EPPPGIVEPS DGEADPR

Length:447

Mass (Da):50,076

Last modified:May 26, 2009 - v1

Checksum:ⁱ3C78478D57632686

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP001332 Genomic DNA. Translation: ACO67331.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002506073.1. XM_002506027.1.

Genome annotation databases

GeneIDⁱ	8248806.
KEGGⁱ	mis:MICPUN_96728.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP001332 Genomic DNA. Translation: ACO67331.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002506073.1. XM_002506027.1.

3D structure databases

ProteinModelPortalⁱ	C1EGI4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GH13. Glycoside Hydrolase Family 13.

CAZyⁱ

GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	8248806.
KEGGⁱ	mis:MICPUN_96728.

Phylogenomic databases

HOGENOMⁱ	HOG000239525.
InParanoidⁱ	C1EGI4.
KEGG Orthology (KO) More...KOⁱ	K01176.

Family and domain databases

InterProⁱ	View protein in InterPro IPR012850. A-amylase_bs_C. IPR006046. Alpha_amylase. IPR006047. Glyco_hydro_13_cat_dom. IPR017853. Glycoside_hydrolase_SF.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07821. Alpha-amyl_C2. 1 hit. PF00128. Alpha-amylase. 1 hit.
PRINTSⁱ	PR00110. ALPHAAMYLASE.
SMARTⁱ	View protein in SMART SM00642. Aamy. 1 hit. SM00810. Alpha-amyl_C2. 1 hit.
SUPFAMⁱ	SSF51445. SSF51445. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C1EGI4_MICCC
Accessionⁱ	C1EGI4Primary (citable) accession number: C1EGI4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 26, 2009
	Last sequence update:	May 26, 2009
	Last modified:	July 5, 2017
	This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - C1EGI4 (C1EGI4_MICCC)

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Alpha-amylase

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Functionⁱ

Catalytic activityⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Protein family/group databases

Names & Taxonomyⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C1EGI4 (C1EGI4_MICCC)

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Alpha-amylase

AMY1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ