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C1DVK9 (C1DVK9_SULAA) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP-Rule MF_00137 RuleBase RU000613
EC=6.3.2.6 HAMAP-Rule MF_00137 RuleBase RU000613
Alternative name(s):
SAICAR synthetase HAMAP-Rule MF_00137
Gene names
Name:purC HAMAP-Rule MF_00137
Ordered Locus Names:SULAZ_1175
OrganismSulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825) [Complete proteome] [HAMAP] EMBL ACN98360.1
Taxonomic identifier204536 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Hydrogenothermaceae › Sulfurihydrogenibium ›

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP-Rule MF_00137 RuleBase RU000613 SAAS SAAS018236

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP-Rule MF_00137 RuleBase RU000613 SAAS SAAS018236

Sequence similarities

Belongs to the SAICAR synthetase family. HAMAP-Rule MF_00137 RuleBase RU004193

Sequences

Sequence LengthMass (Da)Tools
C1DVK9 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 5D118D5AD730E663

FASTA23527,141
        10         20         30         40         50         60 
MEKLYEGKAK IVYKAQDPDK VVIYFKDEAT AFNAQKKDVI EGKGVINNKI SSIFFQILEK 

        70         80         90        100        110        120 
HGIPTHFVKQ LSDREMLAYK TQIIPVEVVV RNLATGSIVK RLGIPEKTPF NPPLIEFYLK 

       130        140        150        160        170        180 
NDQLGDPIIC YEHILALNLA NDQEIKTIKE LAFKVNQILK DILIKHDIIL VDFKLEFGKK 

       190        200        210        220        230 
EDGNIVVADE ISPDTCRFWD AKTGERMDKD RFRLNLGDLA KFYEEVLRRI ENEKD

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Az-Fu1 / DSM 15241 / OCM 825.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001229 Genomic DNA. Translation: ACN98360.1.
RefSeqYP_002729146.1. NC_012438.1.

3D structure databases

ProteinModelPortalC1DVK9.
ModBaseSearch...

Protein-protein interaction databases

STRING204536.SULAZ_1175.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACN98360; ACN98360; SULAZ_1175.
GeneID7673873.
KEGGsaf:SULAZ_1175.
PATRIC23763474. VBISulAzo123226_1138.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0152.
HOGENOMHOG000082629.
KOK01923.
OMAKGWLNAQ.
ProtClustDBPRK09362.

Enzyme and pathway databases

BioCycSAZO204536:GHRE-261-MONOMER.
UniPathwayUPA00074; UER00131.

Family and domain databases

Gene3D3.30.470.20. 1 hit.
HAMAPMF_00137. SAICAR_synth.
InterProIPR013816. ATP_grasp_subdomain_2.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
PANTHERPTHR11609. PTHR11609. 1 hit.
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsTIGR00081. purC. 1 hit.
PROSITEPS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1DVK9_SULAA
AccessionPrimary (citable) accession number: C1DVK9
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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