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C1DT58 (C1DT58_SULAA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HAMAP MF_00823
Short name=ACCase subunit alpha HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA HAMAP MF_00823 EMBL ACN98747.1
Ordered Locus Names:SULAZ_0300
OrganismSulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825) [Complete proteome] [HAMAP]
Taxonomic identifier204536 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Hydrogenothermaceae › Sulfurihydrogenibium

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823 SAAS SAAS011763

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823 SAAS SAAS011763

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823 SAAS SAAS011763

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823 SAAS SAAS011763

Subcellular location

Cytoplasm By similarity HAMAP MF_00823 SAAS SAAS011763.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
C1DT58 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: AB38B8F17438E6C9

FASTA31435,302
        10         20         30         40         50         60 
MDLDRELQNL SDQIEVLRER IKNGEHHLID ELVKLRKTFK KLSEKKMQSL TAWDRVQLAR 

        70         80         90        100        110        120 
HPKRPHTIDY INNIFTDFIE LHGDRRFGDD KAIVAGFANF EGIPVCVIGH EKGKDTKEKI 

       130        140        150        160        170        180 
ERNFGMPHPE GYRKAIRVMK LAEKFKRPVF TFIDTPGAYP GIGAEERGQS QAIAESLMVM 

       190        200        210        220        230        240 
GSLRTPIIAT VIGEGGSGGA LALGVADKIL MLENSIYSVI SPEGCAAILF KSAESAPIAA 

       250        260        270        280        290        300 
ESLKITAKDL LELGVIDCIV REPRGGAHLQ PKKMYRLLKW SLRNALKQVE NIDLDKLVEL 

       310 
RHKKFYSMGR FAEK

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001229 Genomic DNA. Translation: ACN98747.1.
RefSeqYP_002728295.1. NC_012438.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC1DT58.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7673634.
GenomeReviewsGene locus SULAZ_0300 in contig CP001229_GR.
KEGGsaf:SULAZ_0300.
PATRIC23761730. VBISulAzo123226_0291.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGRDTKDN.
ProtClustDBCLSK2479666.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1DT58_SULAA
AccessionPrimary (citable) accession number: C1DT58
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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