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C1DRW0

- PUR5_AZOVD

UniProt

C1DRW0 - PUR5_AZOVD

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAVIN322710:GJ0M-3697-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:Avin_36890
    OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)
    Taxonomic identifieri322710 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
    ProteomesiUP000002424: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 351351Phosphoribosylformylglycinamidine cyclo-ligasePRO_1000212816Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi322710.Avin_36890.

    Structurei

    3D structure databases

    ProteinModelPortaliC1DRW0.
    SMRiC1DRW0. Positions 6-343.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OMAiEFEMYRT.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C1DRW0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKQPSLSYK DAGVDIDAGE ALVERIKGVA RRTARPEVMG GLGGFGALCE    50
    IPAGYRQPVL VSGTDGVGTK LRLAMNLGKH DSIGIDLVAM CVNDLVVCGA 100
    EPLFFLDYYA TGKLNVDVAA RVVAGIGEGC EMAGCALVGG ETAEMPGMYE 150
    GEDYDLAGFC VGVVEKSEII DGAKVAAGDA LIALPSSGPH SNGYSLIRKI 200
    LELSGTDVAG ATLDGKPLAD LLMAPTRIYV KPLLKLIRET GAVKAMAHIT 250
    GGGLTENIPR VLPQGTRAVI DVASWTRPAV FDWLQEKGNV DEREMHRVLN 300
    CGVGMVVCVA RDKVEQALAV LRAAGEQPWL IGDIAAGDGA ERVQLHNLKA 350
    H 351
    Length:351
    Mass (Da):36,801
    Last modified:May 26, 2009 - v1
    Checksum:i17265F8779D892A2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001157 Genomic DNA. Translation: ACO79835.1.
    RefSeqiYP_002800810.1. NC_012560.1.

    Genome annotation databases

    EnsemblBacteriaiACO79835; ACO79835; Avin_36890.
    GeneIDi7762583.
    KEGGiavn:Avin_36890.
    PATRICi21033448. VBIAzoVin72790_3468.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001157 Genomic DNA. Translation: ACO79835.1 .
    RefSeqi YP_002800810.1. NC_012560.1.

    3D structure databases

    ProteinModelPortali C1DRW0.
    SMRi C1DRW0. Positions 6-343.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 322710.Avin_36890.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO79835 ; ACO79835 ; Avin_36890 .
    GeneIDi 7762583.
    KEGGi avn:Avin_36890.
    PATRICi 21033448. VBIAzoVin72790_3468.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OMAi EFEMYRT.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci AVIN322710:GJ0M-3697-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DJ / ATCC BAA-1303.

    Entry informationi

    Entry nameiPUR5_AZOVD
    AccessioniPrimary (citable) accession number: C1DRW0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 22, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3