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C1DRW0

- PUR5_AZOVD

UniProt

C1DRW0 - PUR5_AZOVD

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, Avin_36890
Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-3697-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:Avin_36890
OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)
Taxonomic identifieri322710 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
ProteomesiUP000002424: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_1000212816Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi322710.Avin_36890.

Structurei

3D structure databases

ProteinModelPortaliC1DRW0.
SMRiC1DRW0. Positions 6-343.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

C1DRW0-1 [UniParc]FASTAAdd to Basket

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MSKQPSLSYK DAGVDIDAGE ALVERIKGVA RRTARPEVMG GLGGFGALCE    50
IPAGYRQPVL VSGTDGVGTK LRLAMNLGKH DSIGIDLVAM CVNDLVVCGA 100
EPLFFLDYYA TGKLNVDVAA RVVAGIGEGC EMAGCALVGG ETAEMPGMYE 150
GEDYDLAGFC VGVVEKSEII DGAKVAAGDA LIALPSSGPH SNGYSLIRKI 200
LELSGTDVAG ATLDGKPLAD LLMAPTRIYV KPLLKLIRET GAVKAMAHIT 250
GGGLTENIPR VLPQGTRAVI DVASWTRPAV FDWLQEKGNV DEREMHRVLN 300
CGVGMVVCVA RDKVEQALAV LRAAGEQPWL IGDIAAGDGA ERVQLHNLKA 350
H 351
Length:351
Mass (Da):36,801
Last modified:May 26, 2009 - v1
Checksum:i17265F8779D892A2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001157 Genomic DNA. Translation: ACO79835.1.
RefSeqiYP_002800810.1. NC_012560.1.

Genome annotation databases

EnsemblBacteriaiACO79835; ACO79835; Avin_36890.
GeneIDi7762583.
KEGGiavn:Avin_36890.
PATRICi21033448. VBIAzoVin72790_3468.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001157 Genomic DNA. Translation: ACO79835.1 .
RefSeqi YP_002800810.1. NC_012560.1.

3D structure databases

ProteinModelPortali C1DRW0.
SMRi C1DRW0. Positions 6-343.
ModBasei Search...

Protein-protein interaction databases

STRINGi 322710.Avin_36890.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO79835 ; ACO79835 ; Avin_36890 .
GeneIDi 7762583.
KEGGi avn:Avin_36890.
PATRICi 21033448. VBIAzoVin72790_3468.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci AVIN322710:GJ0M-3697-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DJ / ATCC BAA-1303.

Entry informationi

Entry nameiPUR5_AZOVD
AccessioniPrimary (citable) accession number: C1DRW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: May 14, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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