C1DQD4 (TRPF_AZOVD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	Avin_34210

Organism

Azotobacter vinelandii (strain DJ / ATCC BAA-1303) [Complete proteome] [HAMAP]

Taxonomic identifier

322710 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Azotobacter group › Azotobacter › Azotobacter vinelandii

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 206	206	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000203206

Sequences

	Sequence		Length	Mass (Da)
	C1DQD4 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: B21D34E4378A8859	FASTA	206	21,670
	10 20 30 40 50 60 MAAVRSKICG ITRVEDALVA AEAGVDAIGL VFYPKSPRAV TLRQAKAIVA ALPPFVTAVG 70 80 90 100 110 120 LFVNATRGEV GGILDELPLD LLQFHGDETP ADCEGHGRPY IKALRVRPGE DIAARCLEYC 130 140 150 160 170 180 NASGILLDAY VPGVPGGTGE SFDWSLVPRG LPKPVILAGG LSVRNVRVAI ARVSPYAVDV 190 200 SGGVEAEKGV KDAEKVRAFI REVRNA

References

[1]

"Genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes." Setubal J.C., Dos Santos P., Goldman B.S., Ertesvaag H., Espin G., Rubio L.M., Valla S., Almeida N.F., Balasubramanian D., Cromes L., Curatti L., Du Z., Godsy E., Goodner B., Hellner-Burris K., Hernandez J.A., Houmiel K., Imperial J. , Kennedy C., Larson T.J., Latreille P., Ligon L.S., Lu J., Maerk M., Miller N.M., Norton S., O'Carroll I.P., Paulsen I., Raulfs E.C., Roemer R., Rosser J., Segura D., Slater S., Stricklin S.L., Studholme D.J., Sun J., Viana C.J., Wallin E., Wang B., Wheeler C., Zhu H., Dean D.R., Dixon R., Wood D. J. Bacteriol. 191:4534-4545(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DJ / ATCC BAA-1303.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001157 Genomic DNA. Translation: ACO79570.1.
RefSeq	YP_002800545.1. NC_012560.1.
3D structure databases
ProteinModelPortal	C1DQD4.
ModBase	Search...
Protein-protein interaction databases
STRING	322710.Avin_34210.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACO79570; ACO79570; Avin_34210.
GeneID	7762316.
KEGG	avn:Avin_34210.
PATRIC	21032922. VBIAzoVin72790_3213.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
OMA	PVIRAIQ.
ProtClustDB	PRK01222.
Enzyme and pathway databases
BioCyc	AVIN322710:GJ0M-3422-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_AZOVD

Accession

Primary (citable) accession number: C1DQD4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program